Protein Alignment CG3483 and IDH3B

DIOPT Version :10

• Sequence 1: NP_611912.1
• Gene: CG3483 / 37900
• FlyBaseID: FBgn0035005
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_001317692.1
• Gene: IDH3B / 3420
• HGNCID: 5385
• Length: 387
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 120/349 - (34%)
• Similarity: 204/349 - (58%)
• Gaps: 12/349 - (3%)

  Fly    50 SKGASGKAKSAGSTDSAKKTTKVTLINGEGVGRELMDAVQEVICAVKAPIEWDVH--DEFKAKDS 112
            |..|...::|.......:.:..||::.|:|||.|||.||:||..|...|:|:..|  .|.:...|
Human    29 SAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMAS 93

  Fly   113 DDVSPEVLKSLRANKVGIKGPV--------DSRHWQRQIRKQFAQFAYVSLCSHIEGLDSPYGDF 169
            ::...:||.|::.|||.|.|.:        :...:..::|::...||.|.....:.|..:.:.:.
Human    94 EEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNL 158

  Fly   170 DVVIIRDQMEGDYSGIEHLVVPGVMQTIKVSTTAGAARIAEFVFNYAVKNKRKRITVAHKANIMR 234
            |:||||:|.||:||.:||....||::.:|:.|.|.:.|||:|.|:||.|..|.::|..||||||:
Human   159 DLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMK 223

  Fly   235 MTDGNFLEAMRAEADKHVDDVLFEERYLDTCILKILLKPHKCDVMVSSSMYGDVLRVIAGGMMGV 299
            :.||.||:.....|:.: ..:.||...:|.|.::::..|::.||:|..::||:::..:|.|::|.
Human   224 LGDGLFLQCCEEVAELY-PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGG 287

  Fly   300 PGICPGYSVSSLGTVFDCRMKACHALA-GKDLANPTGPLLSAALMLRHVKMDKQADQVDCAIRKV 363
            .|:.||.|.|:...||:...:...|.| |:::||||..||||:.||||:.::..:..:..|::||
Human   288 AGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKV 352

  Fly   364 YKDTDIRTPDVGGKAKCSEFVKAV 387
            .|...:||.|:||.:..::|:|:|
Human   353 IKVGKVRTRDMGGYSTTTDFIKSV 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3483	NP_611912.1	Iso_dh	71..389	CDD:444908	117/328 (36%)
IDH3B	NP_001317692.1	Iso_dh	47..380	CDD:444908	117/331 (35%)