DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pgam5-2 and BPGM

DIOPT Version :9

Sequence 1:NP_611911.1 Gene:Pgam5-2 / 37899 FlyBaseID:FBgn0035004 Length:280 Species:Drosophila melanogaster
Sequence 2:NP_001280014.1 Gene:BPGM / 669 HGNCID:1093 Length:259 Species:Homo sapiens


Alignment Length:192 Identity:39/192 - (20%)
Similarity:66/192 - (34%) Gaps:54/192 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    81 IILVRHGEYTRTPNG-------SHLTELGRRQAERTGQRLREMGLSWDHVVASTMPRAEETAMII 138
            :|::||||.......       ..|...|..:|...|::|:.:...:|.|..|.:.|:..||.:|
Human     6 LIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVLNRSIHTAWLI 70

  Fly   139 LKQLN-------------------LDPLKMKRCTL--------------------LPEGTPYPGD 164
            |::|.                   |..|..::..|                    :.|..||..:
Human    71 LEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYNVTPPPIEESHPYYQE 135

  Fly   165 PPSKRSARSLDLAYQRDGPR-------IEAAFRRYFFRASPEQEHDSYLLIVGHSNVIRYLI 219
            ..:.|..:..|:...: .||       :|.....:..|.:||......:||..|.|..|.|:
Human   136 IYNDRRYKVCDVPLDQ-LPRSESLKDVLERLLPYWNERIAPEVLRGKTILISAHGNSSRALL 196

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
Pgam5-2NP_611911.1 HP_PGM_like 80..245 CDD:132718 39/192 (20%)
BPGMNP_001280014.1 HP 4..255 CDD:325018 39/192 (20%)
Substrate binding. /evidence=ECO:0000269|PubMed:17052986 10..17 4/6 (67%)