Protein Alignment CG15873 and PRSS3

DIOPT Version :10

• Sequence 1: NP_611910.2
• Gene: CG15873 / 37898
• FlyBaseID: FBgn0035003
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_001184026.3
• Gene: PRSS3 / 5646
• HGNCID: 9486
• Length: 261
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 77/268 - (28%)
• Similarity: 119/268 - (44%)
• Gaps: 41/268 - (15%)

  Fly    18 DADLGVIGDISDETFEMLISGGYKPKSNRLSRHVVSIRTKNYVRHRGDNHFCSGVLVSSRAVLTA 82
            ||.:.|..|..|:     |.|||..:.|.|. :.||:.:        .:|||.|.|:|.:.|::|
Human    25 DALIAVPFDDDDK-----IVGGYTCEENSLP-YQVSLNS--------GSHFCGGSLISEQWVVSA 75

  Fly    83 AHCLTDRYKASMNPRGIRVVFGHITRLAVYDESDFRSVDRLVVHPEYER-YKKNDLAILRLSE-- 144
            |||...|.:..:....|:|:.|:         ..|.:..:::.||:|.| ...||:.:::||.
Human    76 AHCYKTRIQVRLGEHNIKVLEGN---------EQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPA 131

  Fly   145 ----RVQSSNHDVLPLLMRKTANVTYGDTCITLGWGQIYQHG-PYSNELVYLDVILRPPSLCQKH 204
                ||.:.:   ||     |.....|..|:..|||.....| .|.:||..||..:...:.|:..
Human   132 VINARVSTIS---LP-----TTPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKAS 188

  Fly   205 YDTFTADHNVCTEPV-GESMNCAGDMGGPLLCKGALFGLIGGHMGCAGGKAMKFLSFLY-YKDWI 267
            |.....:...|...: |...:|..|.|||::|.|.|.|::....|||........:.:| |.|||
Human   189 YPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWI 253

  Fly   268 LLTIQSLS 275
            ..||.:.|
Human   254 KDTIAANS 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15873	NP_611910.2	Tryp_SPc	59..250	CDD:238113	54/199 (27%)
PRSS3	NP_001184026.3	Tryp_SPc	38..256	CDD:238113	69/243 (28%)