Protein Alignment CG15873 and PRSS2

DIOPT Version :10

• Sequence 1: NP_611910.2
• Gene: CG15873 / 37898
• FlyBaseID: FBgn0035003
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 72/286 - (25%)
• Similarity: 119/286 - (41%)
• Gaps: 42/286 - (14%)

  Fly     3 ILTVFLGLILSTSLSDADLGVIGDISDET---FEMLISGGYKPKSNRLSRHVVSIRTKNYVRHRG 64
            ::..|:...::....|.|..|.|.|.:|.   :::.::.||
Human     5 LILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGY------------------------ 45

  Fly    65 DNHFCSGVLVSSRAVLTAAHCLTDRYKASMNPRG-----IRVVFGHITRLAVYDESDFRSVDRLV 124
              |||.|.|:|.:.|::|.||......:.::.||     |:|..|......:.....|.:..:::
Human    46 --HFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKII 108

  Fly   125 VHPEY-ERYKKNDLAILRLSE-RVQSSNHDVLPLLMRKTANVTYGDTCITLGWGQIYQHG-PYSN 186
            .||:| .|...||:.:::||. .|.:|....:.|   .||....|...:..|||.....| .|.:
Human   109 RHPKYNSRTLDNDILLIKLSSPAVINSRVSAISL---PTAPPAAGTESLISGWGNTLSSGADYPD 170

  Fly   187 ELVYLDVILRPPSLCQKHYDTFTADHNVCTEPV-GESMNCAGDMGGPLLCKGALFGLIGGHMGCA 250
            ||..||..:...:.|:..|.....::..|...: |...:|.||.|||::..|.|.|::....|||
Human   171 ELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCA 235

  Fly   251 GGKAMKFLSFLY-YKDWILLTIQSLS 275
            ........:.:| |.|||..||.:.|
Human   236 QKNRPGVYTKVYNYVDWIKDTIAANS 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15873	NP_611910.2	Tryp_SPc	59..250	CDD:238113	53/199 (27%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	66/260 (25%)