Protein Alignment CG42383 and NSFL1C

DIOPT Version :10

• Sequence 1: NP_523847.2
• Gene: CG42383 / 37897
• FlyBaseID: FBgn0259729
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: XP_011527602.1
• Gene: NSFL1C / 55968
• HGNCID: 15912
• Length: 375
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 116/383 - (30%)
• Similarity: 180/383 - (46%)
• Gaps: 65/383 - (16%)

  Fly     4 EQKLSTFMKRHGVREEVARQYLSSNNWSLEVA-SSTYES--------------EAVSKKQEPEKS 53
            ::.|..|:...|..|:.||.:|.|..|.|::| :|.||.              .:||:...|.:.
Human     6 QEALREFVAVTGAEEDRARFFLESAGWDLQIALASFYEDGGDEDIVTISQATPSSVSRGTAPREK 70

  Fly    54 SEHSQANESNRDLHSLLSEISRRKEGDHDGYQACASDSS------------------------TD 94
            |::...  |.|||.....|....:||....:.|..|:.|                        .:
Human    71 SDNRVT--SFRDLIHDQDEDEEEEEGQRSRFYAGGSERSGQQIVGPPRKKSPNELVDDLFKGAKE 133

  Fly    95 HDTPAGKRVNINSSTPAITNNDSDRSLRVWGHGNRLGSAHPINPPPRSATEDSDTEPADDEHTIV 159
            |...|.:||   :.:|..|:.....:    |.|.|||:|    |...||....:......:...|
Human   134 HGAVAVERV---TKSPGETSKPRPFA----GGGYRLGAA----PEEESAYVAGEKRQHSSQDVHV 187

  Fly   160 VLHLWSEGFSLDDGSLRLYALPENERFLRAILRGDFPEEMLRVP---RVQLSVQDHTNESY--RH 219
            ||.||..|||||:|.||.|..|.|.:||.:|.||:.|.|:.|:.   :|.|.::||.:|.:  ..
Human   188 VLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDFVKPK 252

  Fly   220 LSRKQFMGPGRPLNSPSPQILVVGPMPVEAQ-------GLQLNERADTTTVQLRMADGSRVAGRF 277
            .:.|.|.|.|:.|.|.:||:|.......:|:       .:.::|...||.:|:|:|||.|:..:|
Human   253 GAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLADGGRLVQKF 317

  Fly   278 NLTHNVGDLYQYARLARPEFSDRSFVLMTAFPRQELVESDTRTLVQANLCNVVVIQHL 335
            |.:|.:.|:..:...|||..:..||:|||.||.:||.: :::||.:|||.|.|::|.|
Human   318 NHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELAD-ESQTLKEANLLNAVIVQRL 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42383	NP_523847.2	UBA_TAP-C_like	10..39	CDD:270459	11/29 (38%)
		SEP	155..242	CDD:197786	38/91 (42%)
		UBX_UBXN2	262..334	CDD:340468	29/71 (41%)
NSFL1C	XP_011527602.1	UBA_p47	7..45	CDD:270533	14/37 (38%)
		SEP	183..275	CDD:197786	38/91 (42%)
		UBX_UBXN2C	294..375	CDD:340682	34/82 (41%)