DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42383 and nsfl1c

DIOPT Version :9

Sequence 1:	NP_523847.2	Gene:	CG42383 / 37897	FlyBaseID:	FBgn0259729	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001007447.1	Gene:	nsfl1c / 492805	ZFINID:	ZDB-GENE-041114-160	Length:	372	Species:	Danio rerio

Alignment Length:	382	Identity:	122/382 - (31%)
Similarity:	180/382 - (47%)	Gaps:	65/382 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EQKLSTFMKRHGVREEVARQYLSSNNWSLEVASSTY---------------ESEAVSKKQEPEKS 53
            |:.:..|:....|.||.||.:|.|..|.|::|.:.:               ||.:|::   |...
Zfish     5 EEAVRGFVAVTDVDEERARFFLESAGWDLQLALANFFEDGGEDDIATLPQPESGSVTR---PTGP 66

  Fly    54 SEHSQANESNRDLHSLLSEISRRKEGDHDGYQACASDSSTDHDTPAG--KRVNINSSTPAITN-- 114
            |||...  |.|||.....:.|    ||.:|.:..|..|........|  |:.|.|.....:..
Zfish    67 SEHRVT--SFRDLMHEDDDDS----GDEEGQRFFAGGSERSGQQIVGPPKKKNSNELIEDLFKGA 125

  Fly   115 ---------------NDSDRSLRVWGHGNRLGSAHPINPPPRSAT--EDSDTEPADDEHTI-VVL 161
                           .:|.:|....|.|.|||:|     |...:|  ..:..:|...:..: |||
Zfish   126 KEHGAVPVDKAGKGLGESSKSKPFGGGGYRLGAA-----PEEESTYVAGARRQPGSSQDQVHVVL 185

  Fly   162 HLWSEGFSLDDGSLRLYALPENERFLRAILRGDFPEEM---LRVPRVQLSVQDHTNESYR--HLS 221
            .||..|||||:|.||.|:.|||..||.:|.||:.|.|:   .|..:|.|.::||.:|.:.  .|:
Zfish   186 KLWKTGFSLDEGELRTYSDPENALFLESIRRGEIPLELRQRFRGGQVNLDMEDHRDEDFSKPRLA 250

  Fly   222 RKQFMGPGRPLNSPSPQILVVGPMPVEAQGLQLNERA----DT----TTVQLRMADGSRVAGRFN 278
            .|.|.|.|:.|.|.:|:::.:...|.:....:....|    ||    |::|:|:|||.|:..:||
Zfish   251 FKAFTGEGQKLGSATPELVSLQRSPQDQAASEAEASASISVDTSQPITSIQIRLADGGRLVQKFN 315

  Fly   279 LTHNVGDLYQYARLARPEFSDRSFVLMTAFPRQELVESDTRTLVQANLCNVVVIQHL 335
            .||.|.|:.|:|..|||..:...|||||.||.:||.: :..||.:|||.|.|::|.|
Zfish   316 HTHRVSDVRQFAASARPALAATEFVLMTTFPNKELTD-EGLTLKEANLLNAVIVQRL 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42383	NP_523847.2	UBA_TAP-C_like	10..39	CDD:270459	11/28 (39%)
		SEP	155..242	CDD:197786	38/92 (41%)
		p47_UBX	257..336	CDD:176365	39/87 (45%)
nsfl1c	NP_001007447.1	UBA_p47	5..44	CDD:270533	12/38 (32%)
		SEP	181..270	CDD:197786	38/88 (43%)
		p47_UBX	294..372	CDD:176365	36/79 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576056
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2086
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54012
OrthoDB	1	1.010	-	-		D1175850at2759
OrthoFinder	1	1.000	-	-		FOG0001623
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102041
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.710