DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42383 and p47

DIOPT Version :9

Sequence 1:	NP_523847.2	Gene:	CG42383 / 37897	FlyBaseID:	FBgn0259729	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_610284.1	Gene:	p47 / 35674	FlyBaseID:	FBgn0033179	Length:	407	Species:	Drosophila melanogaster

Alignment Length:	419	Identity:	120/419 - (28%)
Similarity:	189/419 - (45%)	Gaps:	110/419 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LSTFMKRHGVREEVARQYLSSNNWSLEVASSTYES-------------EAVSKKQEPEKSSEHSQ 58
            ::.|::..|..|.|||.||||.:|.:|.|...|.|             .|.:.|.:|..||..|.
  Fly     8 IAQFIEITGTDENVARFYLSSCDWDIEHALGNYWSTQADLPVPVPTVGHADNPKPKPTSSSGASA 72

  Fly    59 A----------------NESNRDL----------HSLLSEISRRKEGDHD--GYQACASDSSTDH 95
            :                :.::.|:          .:.||::|:....|.|  .:.|..||.|...
  Fly    73 SASAAGATKSADSAVATSSASVDIAPAATKAKPKFATLSDMSKESSSDDDQQAFYAGGSDRSGQQ 137

  Fly    96 DTPAGKRVNINSSTPAITNNDSDRSL------------------RVWGHGNRLGSAHPINPPPRS 142
            .....||.|.......:..:..::::                  .|||.|.|||.
  Fly   138 VLGPPKRKNFREQLTDMMRSAQEQNIAEVGPSTSSGSASGGSGGAVWGQGMRLGM---------- 192

  Fly   143 ATEDSDTEPADDEHT---------------IVVLHLWSEGFSLDDGSLRLYALPENERFLRAILR 192
                     .|::||               :|||.|||:|||:|.|.||.|..|:|:.||..::|
  Fly   193 ---------TDNDHTAVGTKKPAATIENKPVVVLKLWSQGFSIDGGELRHYDDPQNKEFLETVMR 248

  Fly   193 GDFPEEMLRVPR-VQLSVQDHTNESYRHLSRKQ-FMGPGRPLNSPSPQILVVGP------MPVEA 249
            |:.|:|:|.:.| |.:.|:||.:|.::.....| |.|.|:.|.||...::...|      .|.||
  Fly   249 GEIPQELLEMGRMVNVDVEDHRHEDFKRQPVPQTFKGSGQKLGSPVANLVTEAPTVPVALSPGEA 313

  Fly   250 --------QGLQLNERADTTTVQLRMADGSRVAGRFNLTHNVGDLYQYARLARPEFSDRSFVLMT 306
                    ..:.||..|.:||:|:|:|||||:|.:|||:|.|.|:.::.:.|||::|..:|:|::
  Fly   314 ANQEASARDAINLNSEAPSTTLQIRLADGSRLAAQFNLSHTVSDIRRFIQTARPQYSTSNFILVS 378

  Fly   307 AFPRQELVESDTRTLVQANLCNVVVIQHL 335
            :||.:|| ..|..|:.:|.|.|..::|.|
  Fly   379 SFPTREL-SDDNSTIEKAGLKNAALMQRL 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42383	NP_523847.2	UBA_TAP-C_like	10..39	CDD:270459	13/28 (46%)
		SEP	155..242	CDD:197786	38/103 (37%)
		p47_UBX	257..336	CDD:176365	34/79 (43%)
p47	NP_610284.1	UBA_ceTYDP2_like	6..42	CDD:270612	14/33 (42%)
		SEP	211..300	CDD:197786	36/88 (41%)
		p47_UBX	329..407	CDD:176365	34/79 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442257
Domainoid	1	1.000	58	1.000	Domainoid score	I7158
eggNOG	1	0.900	-	-		E1_KOG2086
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	73	1.000	Inparanoid score	I3880
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1175850at2759
OrthoFinder	1	1.000	-	-		FOG0001623
OrthoInspector	1	1.000	-	-		mtm1199
orthoMCL	1	0.900	-	-		OOG6_102041
Panther	1	1.100	-	-	P	PTHR23333
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.890