DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42383 and ubxn-2

DIOPT Version :9

Sequence 1:	NP_523847.2	Gene:	CG42383 / 37897	FlyBaseID:	FBgn0259729	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001023590.1	Gene:	ubxn-2 / 177057	WormBaseID:	WBGene00022381	Length:	301	Species:	Caenorhabditis elegans

Alignment Length:	297	Identity:	72/297 - (24%)
Similarity:	115/297 - (38%)	Gaps:	51/297 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 EISRRKEG--DHDGYQACASDSSTDHDTPAGKRVNINSSTPAITNN-DSDRSLRVWGHGNRLGSA 133
            :|....:|  |.|...|.|::.....:..||....:.....|.... ||:..:|     ..|.:|
Worm    10 DIGNNDDGGPDSDDSGADAAERGAPQEFYAGSGQAVQGPRGAAARGPDSEAHIR-----RILQAA 69

  Fly   134 HPINP----PPRSATEDSDTEPADDEHTIVVLHLWSEGFSLDDGSLRLYALPENERFLRAILRGD 194
            ..:.|    .||.       .|:..|...:.|||||:|.|::||.|.....|....||.::.:|:
Worm    70 EVVQPEGGEAPRG-------RPSGRETISLTLHLWSDGLSIEDGPLMSRQDPRTIEFLESVGKGE 127

  Fly   195 FPEEMLRV---PRVQLSVQDHTNESYRHLSRKQFMGPGRPLNSPSPQILVVGPMPVEAQG----- 251
            .|..:::.   ..:...|..| :|.|.....|.|.|.|..|.:..|.:|..........|
Worm   128 IPPSLVQQYPGKEIDFKVNRH-HEEYVAPKMKPFGGSGVRLGNVVPTVLGQSSSSATTAGTSSAT 191

  Fly   252 ----------------------LQLNERADTTTVQLRMADGSRVAGRFNLTHNVGDLYQYARLAR 294
                                  |..|....||.:|:|:.:..|:.|.||.:|.:..:..:...||
Worm   192 TDHNPDHTAENEAKQLEDAKKELSTNMNEPTTNIQIRLPNNQRLVGIFNHSHTLEAVRTFICTAR 256

  Fly   295 PEFSDRSFVLMTAFPRQELVESDTRTLVQANLCNVVV 331
            |:.....|.:|.|:|.:.. |.:::||..||:.|.||
Worm   257 PDMIYAPFQMMAAYPPKPF-EDESQTLKDANVLNSVV 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42383	NP_523847.2	UBA_TAP-C_like	10..39	CDD:270459
		SEP	155..242	CDD:197786	27/89 (30%)
		p47_UBX	257..336	CDD:176365	24/75 (32%)
ubxn-2	NP_001023590.1	SEP	94..164	CDD:311829	22/70 (31%)
ubxn-2	NP_001023590.1	UBQ	220..292	CDD:320785	22/72 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I7158
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	73	1.000	Inparanoid score	I3880
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1175850at2759
OrthoFinder	1	1.000	-	-		FOG0001623
OrthoInspector	1	1.000	-	-		otm14349
orthoMCL	1	0.900	-	-		OOG6_102041
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960