DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42383 and ubxn2a

DIOPT Version :9

Sequence 1:	NP_523847.2	Gene:	CG42383 / 37897	FlyBaseID:	FBgn0259729	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	XP_003200800.2	Gene:	ubxn2a / 100537478	ZFINID:	ZDB-GENE-110411-202	Length:	258	Species:	Danio rerio

Alignment Length:	308	Identity:	78/308 - (25%)
Similarity:	133/308 - (43%)	Gaps:	95/308 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 EAVSKKQEPEKSSEHSQANESNRDLHSLLSEISRRKEGDHDGYQACASDSSTDHDTPAGKRVNIN 106
            |....::|.|:..|.:....|:..:..||.|:.:        ..:.||         :||:|.|
Zfish    18 EGAQNEEEEEEEDEEASPIRSSFSVEDLLDEVEK--------ISSVAS---------SGKKVEI- 64

  Fly   107 SSTPAITNNDSDRSLRVWGHGNRLGSAHPINPPPRSATEDSDTEPADDEHTIVVLHLWSEGFSLD 171
                                                                 |:.||..||:|:
Zfish    65 -----------------------------------------------------VVRLWKNGFTLN 76

  Fly   172 DGSLRLYALPENERFLRAILRGDFPEEM---LRVPRVQLSVQDHTNESYRHLSRKQ----FMGPG 229
            |..||.|...||:.||.||.:|:.|.|:   .....::::|:|..:|.|  :.:|:    |.|.|
Zfish    77 DEDLRSYTQEENQEFLEAIKKGELPLELEGRAEDEELEVNVEDMKDEVY--VPKKKIFHPFTGRG 139

  Fly   230 RPLNSPSPQILV---------VGPMPVEAQGLQLNERADTTTVQLRMADGSRVAGRFNLTHNVGD 285
            ..|.|.:|:::.         .|| ||.|  ::|||....|::|:.:|||.|:..||||.|.:.|
Zfish   140 YRLGSVAPRVVARSRSIHEDCSGP-PVPA--VELNEDLPVTSLQIWLADGRRLVQRFNLCHRISD 201

  Fly   286 LYQYARLARPEFSDRSFVLMTAFPRQELVESDTRTLVQANLCNVVVIQ 333
            :.::...|  :.:|..|:|.|:.|.:||.: :.::|.:|:|.|.|::|
Zfish   202 VQRFVEQA--QITDTPFILTTSLPFRELTD-EAQSLEEADLANAVIVQ 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42383	NP_523847.2	UBA_TAP-C_like	10..39	CDD:270459
		SEP	155..242	CDD:197786	30/102 (29%)
		p47_UBX	257..336	CDD:176365	26/77 (34%)
ubxn2a	XP_003200800.2	SEP	66..139	CDD:285322	25/74 (34%)
ubxn2a	XP_003200800.2	UBQ	175..247	CDD:294102	26/75 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1175850at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010