Protein Alignment SerT and slc6a13

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_001072913.1
• Gene: slc6a13 / 780375
• XenbaseID: XB-GENE-5947897
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 603
• Identity: 251/603 - (41%)
• Similarity: 364/603 - (60%)
• Gaps: 35/603 - (5%)

  Fly    43 DHTTPAKV--------TDPL---APKLANNERILVVSVTERTRETWGQKAEFLLAVIGFAVDLGN 96
            |:..|..|        |.||   .||:.:.:.::       .|..|..|.||:|:|.|..:.|||
 Frog     2 DNKVPGAVSNGYCVPPTKPLMEKEPKMEDGDMMI-------ERGQWNNKVEFVLSVAGEIIGLGN 59

  Fly    97 VWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAIC 161
            ||||||:||:||||||.:||.:||...|:|:|::|.||||:...|.::.|::|||..:|:||:..
 Frog    60 VWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTSQGGVTAWRKICPLFEGIGYSSQ 124

  Fly   162 LIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTENCMQV----TSENFTELATSPAKE 222
            :|.:.:..||..::.||::|||.||||:|||.||.:.||||||:..    ::.|.|...||...|
 Frog   125 VIVMLLNCYYIVVLAWALFYLFNSFTSELPWASCGHSWNTENCLDFYKGNSTHNVTLNGTSSVIE 189

  Fly   223 FFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIIL 287
            |:||:||..  .:|:|.:|.:...||||:...:::.||.:||||:|.||||:.||..||::||:|
 Frog   190 FWERRVLRI--SDGIDNIGGLHWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIVL 252

  Fly   288 LVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRD 352
            |:||||||||..||::||.|:..:|::.:||:||.:|||||.....|.|.||.||||:|||||||
 Frog   253 LIRGVSLPGALTGIQFYLYPDLSRLQDPQVWMDAGTQIFFSYAICLGCLTALGSYNKYNNNCYRD 317

  Fly   353 ALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLVFIVYPEAIATMSGSVFWSII 417
            .:....:|..|||:|||.|||:||:||..|...|..|...||||.||.||.|::.|..|..|:..
 Frog   318 CVALCFLNSGTSFVAGFAIFSILGFMAEEQGVHISDVAESGPGLAFIAYPRAVSMMPFSPLWACF 382

  Fly   418 FFLMLITLGLDSTFGGLEAMITALCDEYPRVIGR--RRELFVLLLLAFIFLCALPTMTYGGVVLV 480
            ||.|:|.|||||.|..:|:::||:.|.||.:..:  ||||.:|.:....||..|..:|.||:.:.
 Frog   383 FFFMVILLGLDSQFVCVESLVTAVVDMYPTIFRKKNRRELLILGVSMISFLVGLIMLTEGGMYVF 447

  Fly   481 NFLNVY-GPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLLTIF 544
            ...:.| ..|:.:|||...|...|.|.||.|.|...||.|:|.:|....:.||.:::|...:..|
 Frog   448 QLFDYYAASGMCLLFVAIFETLCVGWVYGADNFYDKVEHMIGYRPTGIIKYCWLFVTPAVCMATF 512

  Fly   545 IFSIMGYKEM-LGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGCRQRLQESFQPED 608
            :||::.|..: ..:.|.||.|...:||.:..||::|||:::.|| ....||...:|.::...|:.
 Frog   513 LFSLVKYTPLTYNKHYVYPWWGDAIGWLLALSSMVCIPLWVGYK-LSTIKGSLMERFRQLTFPDP 576

  Fly   609 N------CGSVVPGQQGT 620
            :      |..:....|||
 Frog   577 DLPQKTQCEPLSQTAQGT 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	238/540 (44%)
slc6a13	NP_001072913.1	SLC5-6-like_sbd	37..579	CDD:382020	239/544 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010