Protein Alignment SerT and slc6a1a

DIOPT Version :10

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_001038752.2
• Gene: slc6a1a / 692318
• ZFINID: ZDB-GENE-060519-23
• Length: 679
• Species: Danio rerio
• Alignment Length: 534
• Identity: 249/534 - (46%)
• Similarity: 356/534 - (66%)
• Gaps: 5/534 - (0%)

  Fly    74 RETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFH 138
            |||||.|.:|||:.:|:|:.|||||||||:|.:|||||||:||.|.|||.|:|||::|.||||:.
Zfish    43 RETWGGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFFLECALGQYT 107

  Fly   139 RCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTEN 203
            ..|.|.:|| :.|..||||.|..::..::.:||..||.||:|||:.|||:.|||.||:|||||:.
Zfish   108 SIGGLGVWK-LAPMFKGVGLAAAVLSFWLNIYYIVIIAWALYYLYNSFTTDLPWKSCNNPWNTDR 171

  Fly   204 CMQVTSENFTELATSPAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRS 268
            |....|...|...||...||:||.|.:  ..:||:..|.::..||:.:...:|||||.:||||..
Zfish   172 CYTNYSIVDTTNLTSAVMEFWERNVHQ--MTDGLEKPGEIRVPLAITLAIAWVLVYFCIWKGVSW 234

  Fly   269 AGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGF 333
            .||||:.:|..||.:|.||.:|||:||||.|||.:|:||::.|||.|:||:|||:|||||.|.|.
Zfish   235 TGKVVYFSATYPYFMLFILFIRGVTLPGAKEGILFYITPDFEKLKESEVWLDAATQIFFSYGLGL 299

  Fly   334 GTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLVF 398
            |:|:||.|||.||||.|||::|...||..||..|||||||::|:|::|.|..|..|...||||.|
Zfish   300 GSLIALGSYNPFNNNVYRDSIIVCCINSFTSMFAGFVIFSIVGFMSHVTKRPIADVAASGPGLAF 364

  Fly   399 IVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAF 463
            :.||||:..:..|..|:|:||.||:.||:||.|..:|..||||.||:||::.:|||:|:..:...
Zfish   365 LAYPEAVTQLPVSPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEFPRLLRKRREIFIACVCVV 429

  Fly   464 IFLCALPTMTYGGVVLVNFLNVY-GPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLF 527
            .:...|..:|.||:.:....:.| ..|:.:||:||.|...:.|.|||::|..::::|:|.||.::
Zfish   430 SYAIGLSNITQGGLYVFKLFDYYSASGMCLLFLVFFECISISWCYGVNKFYDNIQEMIGYKPCIW 494

  Fly   528 WRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFAS 592
            |::||.:.:|:.:..:|:||.:....:....|.:|.|...|||.:..||::.||.|:.| .|...
Zfish   495 WKLCWVFFTPLVVAGVFLFSAVQMVPLTMNNYVFPKWGQGVGWLMALSSMVLIPGYMGY-MFLNL 558

  Fly   593 KGGCRQRLQESFQP 606
            ||..::|::...||
Zfish   559 KGTYKERIRIMLQP 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	249/534 (47%)
slc6a1a	NP_001038752.2	SLC5-6-like_sbd	2..588	CDD:444915	249/534 (47%)