Protein Alignment SerT and slc6a7

DIOPT Version :10

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_001074049.1
• Gene: slc6a7 / 562050
• ZFINID: ZDB-GENE-070112-1492
• Length: 537
• Species: Danio rerio
• Alignment Length: 581
• Identity: 217/581 - (37%)
• Similarity: 321/581 - (55%)
• Gaps: 65/581 - (11%)

  Fly   120 LIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFA 184
            |.|.|:|||.|||:|||:...|.:::|| .||.|||:|..:..:...:.:|||.||.|..|||.:
Zfish     2 LFFTGMPLFLMELSLGQYGAAGPITVWK-CCPLLKGIGIGMLCVSTLVCLYYNVIIAWTFYYLGS 65

  Fly   185 SFTSKLPWTSCDNPWNTENCMQVTSENFTELATSPAKEFFERKVLESYKGNGLDFMGPVKPTLAL 249
            ||.|.||| |||...|...|     .|.|....||::.|:..|||......||...|||:..|||
Zfish    66 SFQSPLPW-SCDALQNIALC-----ANKTNSTQSPSEVFWNEKVLGVVHSTGLSDPGPVRWPLAL 124

  Fly   250 CVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKN 314
            |:...:::::..:.||:.|:||||::||..||.||::|::||.:|.|:.:|:.:||||:|.:|.:
Zfish   125 CLLAAWIIIFLCMLKGIHSSGKVVYLTATFPYFVLLVLIIRGATLEGSLDGVAFYLTPKWDQLAD 189

  Fly   315 SKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMA 379
            ::||.|||||||:|||.|.|.||:::|||||:||..||.:|.:..||.|||.|||.|||:||:||
Zfish   190 AQVWNDAASQIFYSLGIGVGGLLSMASYNKFDNNVIRDTIIITIGNCSTSFFAGFAIFSILGHMA 254

  Fly   380 YVQKTSIDKVGLEGPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDE 444
            :.:...:|||...||||.|:.||||:|.:.|||||||:|||||..||:|:.||.:|.:.||:.||
Zfish   255 FKKGVPVDKVADSGPGLAFVAYPEALALLPGSVFWSILFFLMLFMLGVDTLFGNMEGICTAVLDE 319

  Fly   445 YPRVIG--RRRELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFY 507
            :|::..  :.:.||:.:|....:|..|..:|.||:.....::.:.....::.:......|:.:||
Zfish   320 FPQLRSNLKHKTLFLAVLCFSFYLMGLLLITDGGIYWFTLIDSFSTSFGLIIITLFMCIGISFFY 384

  Fly   508 GVDRFSSDVEQMLGSKPG------LFWRICWTYISPVFLLTI---FIFSIMGYKEMLGEEYYYPD 563
            ||::|..|:..|:...|.      |:::.||...:| ||||.   :||..|....:....|.||.
Zfish   385 GVNQFCQDIVDMICRCPPWCTKMLLYFKACWVVFTP-FLLTFILTYIFIEMYRTSLRYGSYVYPI 448

  Fly   564 WSYQVGWAVTCSSVLCIPMYIIYKFFFASK--GGCRQRLQESFQPEDNCGSVVPGQQGTSVXHDH 626
            |...:|   .|...||....:|:.....||  |..:.|.::|.:|
Zfish   449 WGKALG---VCMGALCCLQILIWAIVAISKESGTLKDRFKKSIRP-------------------- 490

  Fly   627 AQVHVNIRTSCTSIKIYNLNCSSNSNSLSPTTSGAEGRSCYSTNLNCNHSCPSEDQYRSRN 687
                      ..|.::.|:|.||....:.|.|  .||.  ::.||       :|..|...|
Zfish   491 ----------LNSWRVNNINSSSQEQHVEPHT--IEGP--FTVNL-------TEADYTGMN 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	202/499 (40%)
slc6a7	NP_001074049.1	SLC5-6-like_sbd	1..495	CDD:444915	204/533 (38%)