Protein Alignment SerT and si:ch211-225b11.1

DIOPT Version :10

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_001103931.2
• Gene: si:ch211-225b11.1 / 561694
• ZFINID: ZDB-GENE-060531-39
• Length: 610
• Species: Danio rerio
• Alignment Length: 619
• Identity: 259/619 - (41%)
• Similarity: 375/619 - (60%)
• Gaps: 43/619 - (6%)

  Fly    35 DDSNEDDGDHTTPAKVTDPLAPKLANNERILVVSVTERTRETWGQKAEFLLAVIGFAVDLGNVWR 99
            :...|::...||..:..   |.:|||.|:     .....|||||::.||:||.||:||.||||||
Zfish    24 EGKEEEELARTTTDRAE---ATRLANVEQ-----QAAEPRETWGRRLEFVLATIGYAVGLGNVWR 80

  Fly   100 FPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLID 164
            |||:||::||||||:||.:.|...|:||.:||..:||:.|.|.:....:|||..||||.|..:|.
Zfish    81 FPYLCYRSGGGAFLIPYMIMLFLCGIPLLFMEFTVGQYTRLGPVHALAQICPLFKGVGLATVVIS 145

  Fly   165 IYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNT-ENCMQVTSENFTELATSPAKEFFERKV 228
            ..:..|||.::.||:|||..||:..|||.||:|.||| .||......|.|.| .|.:::||:.||
Zfish   146 YVLCTYYNVLMTWALYYLLHSFSPSLPWQSCNNTWNTVANCSTGFPGNATHL-QSASQQFFDHKV 209

  Fly   229 LESYKGNGLDFMGPVKPTLALCVFGVFVL----VYFSLWKGVRSAGKVVWVTALAPYVVLIILLV 289
            ||  ..:|::..|.|:..|    ||:.||    |||.::|||:|.||||:.||..||.:|..|||
Zfish   210 LE--MTSGIERAGGVRWEL----FGLLVLAWGIVYFCIFKGVKSTGKVVYFTATFPYFILFALLV 268

  Fly   290 RGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDAL 354
            ..|.||||..||.::|.|.|.||...:||::||:|||.|:|..||::::::||||:|||..||..
Zfish   269 NNVQLPGAKNGILFFLMPNWSKLLEVQVWVNAAAQIFNSIGISFGSMISMASYNKYNNNILRDTF 333

  Fly   355 ITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLVFIVYPEAIATMSGSVFWSIIFF 419
            |.|..|..||.:|||||||.:||||::....:|.:..:||||||:||||..:||..|..|:.:||
Zfish   334 IVSLANSATSIVAGFVIFSAIGYMAHIHNLPVDDIATDGPGLVFVVYPEVFSTMPVSQLWAPLFF 398

  Fly   420 LMLITLGLDSTFGGLEAMITALCDEYPR---VIGRRRELFVLLLLAFIFLCALPTMTYGGVVLVN 481
            :||:.|||||.|..:|..:|.:.|.:.|   .:.:|:||.||.:.:|.||..:|.:|.||:.:..
Zfish   399 IMLLCLGLDSQFAMVEVAVTFIMDGFGRKALKVFKRKELIVLAVCSFGFLLGIPHITRGGIYVFQ 463

  Fly   482 FLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLLTIFIF 546
            .::.|...::::|:.|.|...|...:||.|.|..||.|||.||.||:||||.|:||:.:|.|.|.
Zfish   464 LMDHYTAVVSLMFLAFFEVLAVTLIFGVKRLSVMVENMLGKKPNLFFRICWQYLSPMLVLGILIS 528

  Fly   547 SIMGY-KEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGCRQRLQESFQPEDNC 610
            ||:.| ....|:.|.||.|:..:||.::..|::.||:..::: .:.::|...|||::|..|..:.
Zfish   529 SIVQYTPARYGKSYTYPLWAELLGWFISLVSIIWIPLGALHE-LWTTEGSLLQRLKKSITPTVDL 592

  Fly   611 GSVVPGQQGTSVXHDHAQVHVNIRTSCTSIKIYN 644
            .|                  |:.:.|..||.::|
Zfish   593 ES------------------VSEKPSTESIALFN 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	244/541 (45%)
si:ch211-225b11.1	NP_001103931.2	SLC5-6-like_sbd	55..588	CDD:444915	244/540 (45%)