Protein Alignment SerT and slc6a19a.1

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_001091648.1
• Gene: slc6a19a.1 / 553256
• ZFINID: ZDB-GENE-070620-2
• Length: 629
• Species: Danio rerio
• Alignment Length: 626
• Identity: 206/626 - (32%)
• Similarity: 313/626 - (50%)
• Gaps: 102/626 - (16%)

  Fly    56 PKLANNERILVVSVTERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFL 120
            |..:..|::.:....||.:  |..||:::|..:||.|.|||||||||:|..:|||||::|:.:.|
Zfish    15 PSHSELEKLELQEAGERPK--WDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILL 77

  Fly   121 IFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFAS 185
            :..|:||.::|.|:||..|.|.:.:|:.|.|.|.|||.|..|....:|||||||:.|.::|||.|
Zfish    78 VLEGVPLLHLEFAIGQRLRSGSVGVWRSISPYLTGVGIASMLASFIVGMYYNTIMAWVMWYLFNS 142

  Fly   186 FTSKLPWTSCDNPWNTENCMQVTSENFTELA-----TSPAKEFFERKVLESYKGNGLDFMGPVKP 245
            ....|||:.|  |.|.         |.|.|.     :||...|:.|:.|.:  ...::..|.::.
Zfish   143 LQEPLPWSQC--PVNL---------NRTGLVSECERSSPVDYFWYRETLNT--STAIEDSGALQW 194

  Fly   246 TLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWH 310
            .|.||:...:..:|....:|:.:.||.|::|:..|||||.|.|:|.::|.|:..|||:..||:.:
Zfish   195 WLVLCLLCAWTFLYICCIRGIETTGKAVYITSTLPYVVLTIFLIRALTLKGSVNGIKFLFTPDVN 259

  Fly   311 KLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVL 375
            :|.|...|:||.:|:.||....||.|::.||||..:|||.:||:..|.||.|||..:..||:|::
Zfish   260 ELMNPSTWLDAGAQVLFSFSLAFGGLISFSSYNSVHNNCEQDAVTISIINGLTSVYSATVIYSII 324

  Fly   376 G---------------------------------YMAYVQKTSIDK------------------- 388
            |                                 |...:|:.:|.:
Zfish   325 GFRATENYDICLDSNILSLLNAFDLPEGSITENNYTVALQQLNISRPDIIQELQLKTCDMQTLLS 389

  Fly   389 VGLEGPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCD------EYPR 447
            .|:||.||.|||:.|||..|..|..||::||:||..|||.:.||.:|.::..|.|      .:|
Zfish   390 EGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSTMFGNIEGVVVPLQDLNLLPKRWP- 453

  Fly   448 VIGRRRELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRF 512
                 :|:|..|.....||.||..:...|...:...:.:...:.:|.:...|...|.:.||:|||
Zfish   454 -----KEVFTGLTCVVSFLTALVFVQSSGNYWLALFDGFAGSIPLLVIALCELIAVVYVYGIDRF 513

  Fly   513 SSDVEQMLGSKPGLFWRICWTYISPVFLLTIFIF-SIMGYKEMLG--------------EEYYYP 562
            :.|::.|:|.||.:||:|.|.::|||.||.|.|| .|....:.|.              :|..||
Zfish   514 NEDIKFMVGHKPNIFWQISWRFLSPVILLVILIFYFITTVSKQLTYNVWDPQSADFPTLKEVDYP 578

  Fly   563 DWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGCRQRLQES 603
            :|...|.:.:.....||||...|.:..:..   |.:|..:|
Zfish   579 NWISVVIFVLAGVPSLCIPGVAIGRALWRC---CTRRKHKS 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	202/608 (33%)
slc6a19a.1	NP_001091648.1	SLC5-6-like_sbd	31..611	CDD:294310	201/603 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810