Protein Alignment SerT and RGD1562492

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_001102616.1
• Gene: RGD1562492 / 499151
• RGDID: 1562492
• Length: 743
• Species: Rattus norvegicus
• Alignment Length: 665
• Identity: 173/665 - (26%)
• Similarity: 295/665 - (44%)
• Gaps: 136/665 - (20%)

  Fly    21 PAPWSDDKESPNNEDDSNEDDGDHTTPAKVTDPLAPKLANNERILVVSVTERTRETWGQKAEFLL 85
            |.|   .||.|..|:.        |...|.|||.:  |:...:...|.:|:.:.....:|.|.:|
  Rat     9 PEP---KKEEPTEEEP--------TASKKSTDPTS--LSWGFKTREVRITKISSHFQAKKTENIL 60

  Fly    86 AVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRIC 150
            .::.|::.||:.|||||:|:|||||:||:.|.:.|:..|:||.|||:.:||:.|...:..||.:.
  Rat    61 ILVAFSIGLGSTWRFPYLCHQNGGGSFLLMYLILLLLLGIPLMYMEMVIGQWLRVDNIRAWKHLV 125

  Fly   151 PALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTENCMQVTSENFTE- 214
            |.|.||||:..|....:.:|.:.::.|:::||..||....||         |||..|  :||:.
  Rat   126 PWLSGVGYSSMLACALVILYNSALVSWSLFYLGQSFDYPTPW---------ENCPLV--KNFSTS 179

  Fly   215 ----LATSPAKEFFERKVLESYK--GNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVV 273
                |.|.|.:.|:...||.:..  ..|::.:   ...:.||:|..:..:|.::...::.:..::
  Rat   180 DISCLRTEPHQFFWYHTVLRASDQIEEGIEVL---VLNVTLCLFATWFFLYITMVTRIKISVLMM 241

  Fly   274 WVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLA 338
            ..:.|.|.|:|.........:.|..:.:|..:|.|...|.:...|..|...:.:|||.|.||::.
  Rat   242 IFSILFPNVLLFCFFTHIFFVKGVRDSLKRLVTTELSILASLDAWRQAGGHVLYSLGLGMGTIIT 306

  Fly   339 LSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGY-------------------------- 377
            .|||.....|..:.|...:.:|.:||.|:..|||.:||:
  Rat   307 FSSYQTRGENYIKWASFVAMVNLMTSLLSSSVIFLMLGFWIENSGTPCVESNVSNLLSLIANGVL 371

  Fly   378 --MAYVQKTSIDKVGL----------------------------------EGPGLVFIVYPEAIA 406
              :|:..|..|.:..|                                  |||||.::.:.:||.
  Rat   372 PQVAWPPKDIIHRSPLEYLDWISQLPKNIRNEVAHFTLPCSILVQKEKFMEGPGLAYVAFSQAIT 436

  Fly   407 TMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITAL------CDEYPRVIGRRRELFVLLLLAFIF 465
            ...||.||:||||:.|:.:||.:....:|.:..:|      .:::|:::.      |::.|.. |
  Rat   437 LFPGSSFWAIIFFMSLVIMGLGTMTTLVEGIALSLQKSISTLEKHPKLVP------VIICLGG-F 494

  Fly   466 LCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFW-- 528
            |.:|...:..|..:|...:.:...:.::.:|..:...:.|.||:.||.:   :|.|....|.|
  Rat   495 LGSLVFSSRPGSYVVFLFDDHLVPMVLIMIVAFQNLSLAWVYGIKRFRA---EMFGQLGRLVWAP 556

  Fly   529 -RICWTYIS-PVFLLTIFIFSIMGYKEMLGEEYYYPDWS----------YQ---VGWAVTCSSVL 578
             ...|:|:: |..|:.:.|:.:..|   ..|...|..|:          ||   :|| ||..|||
  Rat   557 FTFLWSYVTLPTLLVLLTIYFLNLY---FSESLSYVSWNNSMSQEVKQPYQRIALGW-VTFLSVL 617

  Fly   579 C---IPMYIIYKFFF 590
            .   ||||.:..:::
  Rat   618 ALLPIPMYPLQHWWY 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	159/612 (26%)
RGD1562492	NP_001102616.1	SLC5-6-like_sbd	50..621	CDD:382020	155/598 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820