Protein Alignment SerT and slc6a1b

DIOPT Version :10

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_001007363.1
• Gene: slc6a1b / 492490
• ZFINID: ZDB-GENE-041114-57
• Length: 600
• Species: Danio rerio
• Alignment Length: 557
• Identity: 256/557 - (45%)
• Similarity: 364/557 - (65%)
• Gaps: 9/557 - (1%)

  Fly    55 APKLANNERILVVSVTER----TRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVP 115
            ||...:..:.|||.|.::    .||||..|.:|||:.:|:|:.|||||||||:|.:|||||||:|
Zfish    20 APTANDKPKTLVVKVQKKKELPDRETWQGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIP 84

  Fly   116 YCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVY 180
            |.|.|||.|:|||::|.||||:...|.|.:|| :.|..||||.|..::..::.:||..||.||:|
Zfish    85 YFLTLIFAGVPLFFLETALGQYTSIGGLGVWK-LAPMFKGVGLAAAVLSFWLNIYYIVIIAWAIY 148

  Fly   181 YLFASFTSKLPWTSCDNPWNTENCMQVTSENFTELATSPAKEFFERKVLESYKGNGLDFMGPVKP 245
            ||:.|||:.|||.||||||||:.|....|.......||...||:||.:.:  ..:||:..|.::.
Zfish   149 YLYNSFTTDLPWKSCDNPWNTDKCFSNYSMANIGNMTSAVVEFWERNMHQ--LTDGLEKPGEIRL 211

  Fly   246 TLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWH 310
            .||:.:...:|||||.:||||...||||:.:|..||.:|.||.:|||:||||.|||.:|:|||:.
Zfish   212 PLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYFMLFILFIRGVTLPGAKEGILFYVTPEFS 276

  Fly   311 KLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVL 375
            |||.|:||:|||:|||||.|.|.|:|:||.|||.||||.|:|::|...||..||..|||||||::
Zfish   277 KLKESEVWLDAATQIFFSYGLGLGSLIALGSYNPFNNNVYKDSIIVCCINSFTSMFAGFVIFSIV 341

  Fly   376 GYMAYVQKTSIDKVGLEGPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITA 440
            |:||::.|..|..|...||||.|:.||||:..:..|..|:::||.||:.||:||.|..:|..|||
Zfish   342 GFMAHITKRPIADVAASGPGLAFLAYPEAVTQLPISPLWAVLFFSMLLMLGIDSQFCTVEGFITA 406

  Fly   441 LCDEYPRVIGRRRELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVY-GPGLAILFVVFVEAAGVF 504
            |.||:||.:..|||:|:.::....:|..|..:|.||:.:....:.| ..|:.:||:||.|...:.
Zfish   407 LVDEFPRALRGRREIFIAVVCLVSYLIGLSNITQGGLYVFKLFDYYSASGMCLLFLVFFECVSIS 471

  Fly   505 WFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVG 569
            |||||::|..::|:|:|.||.::|::||...:|:.:..:|:||.:....:....|.:|.|...||
Zfish   472 WFYGVNKFYGNLEEMIGYKPCIWWKLCWVVFTPLIVAGVFLFSAVQMVPLTLNNYVFPKWGQGVG 536

  Fly   570 WAVTCSSVLCIPMYIIYKFFFASKGGCRQRLQESFQP 606
            |.:..||::.||.|:.| .|...||..::||:...||
Zfish   537 WCMALSSMVLIPGYMGY-MFLTLKGSYKERLRIMIQP 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	250/534 (47%)
slc6a1b	NP_001007363.1	SLC5-6-like_sbd	2..600	CDD:444915	256/557 (46%)