DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SerT and CG15279

DIOPT Version :9

Sequence 1:	NP_001369117.1	Gene:	SerT / 37895	FlyBaseID:	FBgn0010414	Length:	768	Species:	Drosophila melanogaster
Sequence 2:	NP_609726.1	Gene:	CG15279 / 34863	FlyBaseID:	FBgn0028886	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	606	Identity:	208/606 - (34%)
Similarity:	325/606 - (53%)	Gaps:	44/606 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 DDGDHTTPAKVTDPLAPKLANNERILVVSVTERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYIC 104
            |||..|.........:|.|.:|......:.....|.|||:..|||::.|..:|.||||||||:..
  Fly    16 DDGRSTASTVEISTNSPALRDNSDDQEAAKVPEERATWGKGVEFLMSCIAMSVGLGNVWRFPFTA 80

  Fly   105 YQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGM 169
            ..|||||||:||.:.|...|.|::|:|:.:|||...|.:.::. :|||:||||.........:..
  Fly    81 LDNGGGAFLIPYLIVLFLIGKPIYYLEMVIGQFSSRGSVKVFD-LCPAMKGVGAGQAFQVFMLST 144

  Fly   170 YYNTIIGWAVYYLFASFTSKLPWTSCDNPW---------NTENCMQVTS-----ENFT-----EL 215
            ||..::.....|...||.:.|||::|...|         :..|..|:.|     :|:|     :.
  Fly   145 YYAALVAIIGRYFIESFRNPLPWSTCRAEWGIHCINSAPDASNWSQLESNDQRPQNYTMKSQNDR 209

  Fly   216 ATSPAKEFFERKVLES----YKGNGLDFMGPVKPTLALCVFGVFV---LVYFSLWKGVRSAGKVV 273
            ..:.::.:|.::||..    .:|.||       |...| |.|:|:   .|:|.:.:||:|:||..
  Fly   210 VITSSEWYFVKEVLHEKPNIEEGIGL-------PNWEL-VIGLFIAWSCVFFIIRRGVKSSGKAS 266

  Fly   274 WVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLA 338
            :..||.|||::.:||||.|:|||:.:||.|::.|:|.|:.:.|||..|.:|.|:||...||.::.
  Fly   267 YFLALFPYVIMGVLLVRAVTLPGSIDGIYYFIKPQWGKILDPKVWYAAVTQCFYSLSVCFGNIIM 331

  Fly   339 LSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAY-VQKTSIDKVGLEGPGLVFIVYP 402
            .||:|||.:|.:|||.|.:.::.:||.||||.||.:||::|: :....|..|...|.||.||.||
  Fly   332 YSSFNKFGHNVHRDAAIVTGLDTMTSLLAGFTIFGILGHLAHEIGTDDIGSVVKGGAGLAFISYP 396

  Fly   403 EAIATMSG--SVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAFI- 464
            :|||....  .:| |::|||||..||:.|........:||:.|.:|. .|:.:   ..||:|.:
  Fly   397 DAIAKFKNLPQIF-SVLFFLMLFVLGIGSNIAMTSCSVTAIRDRFPN-FGQWQ---CSLLIAVVS 456

  Fly   465 FLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWR 529
            |...|..:|.||..::..::.:|..:..|.:...|...:.|.||.||...|:|.|||.|.||:||
  Fly   457 FFIGLMYITPGGQYMLTLVDFFGASMIALVLGIAELYTIGWIYGTDRLCKDIEFMLGRKVGLYWR 521

  Fly   530 ICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKG 594
            :||:.|:|:.:..|.|:....|:.:......||:|||.:||.:|...:|.:|:::|.........
  Fly   522 LCWSIITPLIMTVILIYFYATYQPLTYNNIVYPNWSYSIGWLITAFGILQLPIWMIVAIVRDPGQ 586

  Fly   595 GCRQRLQESFQPEDNCGSVVP 615
            ....:::.:|.|:.|.|...|
  Fly   587 TLGAKIRGAFTPKKNWGPSDP 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	197/562 (35%)
CG15279	NP_609726.1	SLC5-6-like_sbd	50..598	CDD:294310	197/561 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440741
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850