Protein Alignment SerT and CG13795

DIOPT Version :10

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_609138.3
• Gene: CG13795 / 34049
• FlyBaseID: FBgn0031937
• Length: 594
• Species: Drosophila melanogaster
• Alignment Length: 596
• Identity: 144/596 - (24%)
• Similarity: 264/596 - (44%)
• Gaps: 87/596 - (14%)

  Fly    53 PLAPKLANNERILVVSVTERTRETWGQKAEFLLAVIGFAVDL----GNVWRFPYICYQNGGGAFL 113
            |.:|.|              .|..|.:..:|:.|..|.|:.|    .:.|.|     .:.|...:
  Fly    13 PFSPDL--------------NRGKWDKPTDFMFACFGLALKLDVFVASFWMF-----FDMGILGI 58

  Fly   114 VPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWA 178
            :||.:::....:|:..:...:|||...|.:|.: |:.|..||:||....:.|.|.:||:......
  Fly    59 LPYFVYMSIYLVPIMVIHSFMGQFSSSGFISAF-RLSPFFKGMGYVSGFLTISMLIYYSIFAAVP 122

  Fly   179 VYYLFASFTSKLPWTSCD--NPWNTENCMQVTS-------ENFTELATS------PAKEFFER-- 226
            :.::..||...||| ||:  :.|:..:....:|       |:|:|...|      |:..:|:.
  Fly   123 LLFIINSFRPTLPW-SCEGLSSWHNGSATLSSSCNKTLILEDFSEYNRSHQLLHVPSVLYFQNHY 186

  Fly   227 ------KVLESYKGNGLD--FMGPVKPTLALCVFG-VFVLVYFSLWKGVRSA--GKVVWVTALAP 280
                  .|.:.||...|.  |:|         :|. ::|::.|..:|...:|  ||::....:..
  Fly   187 DSMQQDAVPDWYKDYELSWHFVG---------LFAIIWVVIAFIFYKFSETAKFGKLIRYMVIVT 242

  Fly   281 YVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAAS---QIFFSLGPGFGTLLALSSY 342
            .|:|::..||.:.||||..|:..|:||     |.|.:.:...|   .:..:.|.|:|:::.|||:
  Fly   243 LVLLLVCFVRFLFLPGALNGLHRYVTP-----KASDMAMGVVSTFIMVLHAFGAGWGSVITLSSF 302

  Fly   343 NKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVG-LEGPGLVFIVYPEAIA 406
            |.|..:....:.|.|........:.|.|.|.:..|  :.:.:.:|..| :....|:::....|::
  Fly   303 NGFKTDIMSYSWIISFGQIFIYIMFGMVSFMLEHY--FNELSDVDDNGHVLSHWLLYLSSASALS 365

  Fly   407 TMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAFIFLCALPT 471
            ||:....|:.|::.||:...|......:..::.:|.||: .|:..|::.....|:..|.||:...
  Fly   366 TMAWPNLWTFIYYSMLLIAALIVMTTQIFTVLQSLFDEF-EVLRVRKQEVTFGLIGGIALCSFYF 429

  Fly   472 MTYGGVVLVNFLN---VYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRI-CW 532
            .|..|::..:.|.   ::...|..|.::.|    |.|.||.:||..|:|.||| :|...|:: ..
  Fly   430 CTNHGIIFFSALGLDAIFSHSLLHLLLLLV----VLWIYGRERFQRDIEFMLG-QPFASWKVFIL 489

  Fly   533 TYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGCR 597
            .:|:|:.|:   |..:.|....:.|..|.....:.:...:....:|.||.|..| :.:.|.|...
  Fly   490 RFIAPIILV---ICLLAGIALSISEHSYSTTVVFVMSIVLVVLPILAIPGYGFY-YLYQSTGTFC 550

  Fly   598 QRLQESFQPED 608
            :|.:.:.:|.|
  Fly   551 ERFKRTCRPTD 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	139/572 (24%)
CG13795	NP_609138.3	SLC5-6-like_sbd	27..505	CDD:271356	126/509 (25%)