Protein Alignment SerT and NAAT1

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Alignment Length: 645
• Identity: 206/645 - (31%)
• Similarity: 326/645 - (50%)
• Gaps: 87/645 - (13%)

  Fly     4 SGSSDFAGAAATTGRSNPAPWSDDKESPNNEDDSNEDDGDHTTPAKVTDPLAPKLANNERILVVS 68
            :|||:.:|..||...|..   ..|.|.|..|
  Fly    10 NGSSNGSGNGATNAASTE---KTDAEKPTAE---------------------------------- 37

  Fly    69 VTERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELA 133
                 |..||...|||::.|..:|.||||||||:..|:|||||||:||.:.|...|.|::|:|:.
  Fly    38 -----RTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMI 97

  Fly   134 LGQFHRCGCLSIWKRICPALKGVGY-----AICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWT 193
            :|||...|.:.||. :.|...||||     .||:|.     ||::::...:||||.||.|:|||:
  Fly    98 MGQFTSQGTVKIWS-VVPGFVGVGYGQAFGTICIIS-----YYSSLLALTLYYLFVSFQSELPWS 156

  Fly   194 SCDNPWNTENCMQ--------------------------VTSENFTELATSPAKEFFERKVLESY 232
            .|.:.|.  ||:.                          :.:.:.||...|.::.:|...|::.
  Fly   157 YCRDEWT--NCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSSELYFLNVVIKE- 218

  Fly   233 KGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGA 297
            |.:..|.:|.....|.|.:|..:|:::..:.:||:|:||..:..||.|||||.:||:|.|:|.||
  Fly   219 KLDISDGVGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGA 283

  Fly   298 DEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCL 362
            .:||.::|.|:|.:|.|..||.:|..|.||||..|.|.::..:|||:|::..||||:|.::::.|
  Fly   284 RDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTL 348

  Fly   363 TSFLAGFVIFSVLGYMAY-VQKTSIDKVGLEGPGLVFIVYPEAIATMSG-SVFWSIIFFLMLITL 425
            ||.|.|..||::||.:|: :|..:|..|...|.||.||.||:||:.... ...:|::||.||..|
  Fly   349 TSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVL 413

  Fly   426 GLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVYGPGL 490
            |:.|.......::|.:||::.   |.:.....|......||..|..:|.||..::..::.||...
  Fly   414 GIGSIVALQSTIVTIICDQFK---GWKYWKVALTTSVCGFLMGLVYVTPGGQWILTLVDFYGGTY 475

  Fly   491 AILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEML 555
            .:..:...|.||:.|.||:..|..|:|.|...:..|:||:||::.:||.::.|||:|::..:.:.
  Fly   476 VVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMIIIFIYSMVTIEPIK 540

  Fly   556 GEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGCRQRLQESFQPEDNCGSVVP 615
            ..|.|:|:.:...||.:........|::.::......:|...:.|:.|.:|.|..|...|
  Fly   541 YSELYFPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKSLKASLKPSDRWGPANP 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	191/565 (34%)
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	180/504 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440742
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850