Protein Alignment SerT and Slc6a14

DIOPT Version :10

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_038955501.1
• Gene: Slc6a14 / 298340
• RGDID: 1561810
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 613
• Identity: 252/613 - (41%)
• Similarity: 367/613 - (59%)
• Gaps: 48/613 - (7%)

  Fly    44 HTTPAKVTDPLAPKLANNERILVVSVTE-RTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQN 107
            |....|||       |::|...|....| :.|..|.:|:::||:::|:||.|||||||||:.|.|
  Rat    18 HRFCQKVT-------ASSENFHVGENDENQERGNWSKKSDYLLSMVGYAVGLGNVWRFPYLTYTN 75

  Fly   108 GGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYN 172
            ||||||:||.:.|...|||||::|.:||||...|.:|:| ||.|..:|||..:.||.|::.:|||
  Rat    76 GGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVW-RILPLFQGVGITMVLISIFVTIYYN 139

  Fly   173 TIIGWAVYYLFASFTSKLPWTSCDNPWNTENCMQ-----------------------VTSENFTE 214
            .||.:::|||||||.|.|||.:|.:.|..:||.:                       |.|.|||.
  Rat   140 VIIAYSLYYLFASFQSVLPWANCSSSWADDNCSRQPIVTGCRVSTDTGGDMFMNISWVNSNNFTC 204

  Fly   215 LATS--------PAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGK 271
            |..|        |:::::::..|.  :.:|:|..|.:...||||:...:::|..:|:||::|:||
  Rat   205 LNGSEVFRPGQLPSEQYWDKVTLR--RSSGMDETGVIVWYLALCLLLAWIIVGAALFKGIKSSGK 267

  Fly   272 VVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPE--WHKLKNSKVWIDAASQIFFSLGPGFG 334
            ||:.|||.|||||:|||:||.:|.||.:||.||:..:  :.||:.::||.|||:|||:||...:|
  Rat   268 VVYFTALFPYVVLLILLIRGATLEGASKGISYYIGAQSNFTKLREAEVWKDAATQIFYSLSVAWG 332

  Fly   335 TLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLVFI 399
            .|:|||||||||||||.||:|....|||||..|||.|||:||:||::....:.:|...|..|.||
  Rat   333 GLVALSSYNKFNNNCYSDAIIVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFI 397

  Fly   400 VYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAFI 464
            .||||:|.:.|..||||:||.||:||||||.|..:|.:.|.:.|.:|:.:.|.|....|.....:
  Rat   398 AYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKAMKRMRVPITLGCCLIL 462

  Fly   465 FLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLF-- 527
            ||..|..:|..|:..|:.::.:..|..||....:|.||:.|.||.:||..|:|.|:|:|..||
  Rat   463 FLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILEIAGIIWIYGGNRFIEDIEMMIGAKRWLFWL 527

  Fly   528 -WRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFA 591
             ||.||..|:|:.|..|.::|::.:......:..||||...:||.:....::.||:..|.|...|
  Rat   528 WWRACWFVITPILLSAILVWSLVKFHRPNYADIPYPDWGVALGWCMIIFCIIWIPIMAIIKIVRA 592

  Fly   592 SKGGCRQRLQESFQPEDNCGSVVPGQQG 619
             :|...||:.:..:|..|.|..:...:|
  Rat   593 -EGNILQRIIKCCRPASNWGPYLEKHRG 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	240/568 (42%)
Slc6a14	XP_038955501.1	SLC6sbd_ATB0	42..645	CDD:271391	244/582 (42%)