Protein Alignment SerT and Slc6a7

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_006525992.1
• Gene: Slc6a7 / 240332
• MGIID: 2147363
• Length: 684
• Species: Mus musculus
• Alignment Length: 547
• Identity: 244/547 - (44%)
• Similarity: 342/547 - (62%)
• Gaps: 12/547 - (2%)

  Fly    74 RETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFH 138
            |..|..|.:|||:.||:.|.|||||||||..|.||||||||||.|.|...|:|||::||:||||.
Mouse    84 RGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFS 148

  Fly   139 RCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTEN 203
            ..|.|::|| |.|..||.|.|:.||...:.:|||.||.:.::|||||.||.|||..|.|.||||.
Mouse   149 SLGPLAVWK-ISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSNLPWEHCGNWWNTEL 212

  Fly   204 CMQ---------VTSENFTELATSPAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVY 259
            |::         |...|.:. ..||::|::.|.||......|:...|.::..|.||:...:|:|:
Mouse   213 CLEHRGPKSGNGVLPLNLSS-TVSPSEEYWSRYVLHIQGSQGIGRPGEIRWNLCLCLLLAWVIVF 276

  Fly   260 FSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQ 324
            ..:.|||:|:||||:.||..||::|::||||||:||||.:||::||||::|.|.:|||||:||.|
Mouse   277 LCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQ 341

  Fly   325 IFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKV 389
            ||:|||.|||.||..:|||.|:.|.|||..|.:..|.:||.||||.||||||||:......:|:|
Mouse   342 IFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQV 406

  Fly   390 GLEGPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRE 454
            ...||||.|:|||:|:..:..|.|||.:||.||:||||||.|..||.::||:.||:|..:..::.
Mouse   407 AKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKA 471

  Fly   455 LFVLLLLAFIFLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQM 519
            :|..|:...::|..|...|.||:..:..|:.|.....::.||......|...||:.||..|:..|
Mouse   472 VFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMM 536

  Fly   520 LGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYI 584
            ||.||||::|.||.::||..||.:.::||:.|:......|.:|.|:..:|..:...|.|.||..:
Mouse   537 LGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPAWAELLGILMGLLSCLMIPAGM 601

  Fly   585 IYKFFFASKGGCRQRLQESFQPEDNCG 611
            :.. ....:|...:|||::.:|..:.|
Mouse   602 LVA-VLREEGSLWERLQQASRPAMDWG 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	242/541 (45%)
Slc6a7	XP_006525992.1	SLC5-6-like_sbd	84..628	CDD:382020	244/547 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820