Protein Alignment SerT and Slc6a18

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_001035782.1
• Gene: Slc6a18 / 22598
• MGIID: 1336892
• Length: 615
• Species: Mus musculus
• Alignment Length: 579
• Identity: 212/579 - (36%)
• Similarity: 302/579 - (52%)
• Gaps: 82/579 - (14%)

  Fly    71 ERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALG 135
            |..|..|..|.::||:.|||||.|||:|||||:|..:||||||:||.:.|:|.|:||||:|||:|
Mouse    14 EDERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCQTHGGGAFLIPYFIALVFEGIPLFYIELAIG 78

  Fly   136 QFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWN 200
            |..|.|.:.:||.|.|.|.|||.....:...:.:||||::.|.:::...||...|||::|....|
Mouse    79 QRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTVLLWVLWFFLNSFQHPLPWSTCPLDLN 143

  Fly   201 TENCMQVTSENFTELATSPAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKG 265
            ....:|....:.|      ...|:.|:.|..  .:.:...|.::..|.||:...:..||..:.:|
Mouse   144 RTGFVQECQSSGT------VSYFWYRQTLNI--TSDISNTGTIQWKLFLCLVACWSTVYLCVIRG 200

  Fly   266 VRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLG 330
            :.|.|||::.|||.||:||.|.|:||::||||.||:.|..||....|:|.:||:|||:||||||.
Mouse   201 IESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLIYLFTPNMKTLQNPRVWLDAATQIFFSLS 265

  Fly   331 PGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMA---------------- 379
            ..||..:|.:|||...|||.:||:|.:.:|.:||..|...||||:|:.|
Mouse   266 LAFGGHIAFASYNPPRNNCEKDAVIIALVNSMTSLYASIAIFSVMGFKASNDYGRCLDRNILSLI 330

  Fly   380 --------------------YVQKTSIDKVG--------LE--------GPGLVFIVYPEAIATM 408
                                |:..|...:|.        ||        ||||.|||:.||:..|
Mouse   331 NEFDLPELSISRDEYPSVLMYLNATQTARVAQLPLKTCHLEDFLDKSASGPGLAFIVFTEAVLHM 395

  Fly   409 SGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAFIFLCALP-TM 472
            .|:..||::||.||.||||.|.||.:|.:||.|.|......|..:|:...::....||.|:. |:
Mouse   396 PGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLLDMGILPKGIPKEVMTGVICFACFLSAICFTL 460

  Fly   473 TYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISP 537
            ..||..|..| :.:...|.::...|:|..||...||:.||..|:|.|.|.:|||:|::.|..:||
Mouse   461 QSGGYWLEIF-DSFAASLNLIIFAFMEVVGVIHIYGMKRFCDDIEWMTGRRPGLYWQVTWRVVSP 524

  Fly   538 VFLLTIFIFSIM-------GYKEM--------LGEEYYYPDWSYQVGWAVTCSSVLCIP 581
            :.|..||:..|:       .||..        ..||.:||.|.     .|||..:..:|
Mouse   525 MLLFGIFLSYIVLLIQTPPSYKAWNPQYEHFPSREEKFYPGWV-----QVTCVLLSFLP 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	211/576 (37%)
Slc6a18	NP_001035782.1	SLC6sbd_B0AT3	16..591	CDD:212086	211/577 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810