Protein Alignment SerT and snf-11

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_505873.2
• Gene: snf-11 / 191770
• WormBaseID: WBGene00004910
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 588
• Identity: 229/588 - (38%)
• Similarity: 349/588 - (59%)
• Gaps: 54/588 - (9%)

  Fly    68 SVTERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMEL 132
            ||.|  ||.|...|:|:::.||:|:.|||||||||:||||||||||:|||:.|:|.|.|||.:|.
 Worm     6 SVAE--REQWSSWADFIMSCIGYAIGLGNVWRFPYLCYQNGGGAFLIPYCISLVFCGAPLFILET 68

  Fly   133 ALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFT-SKLPWTSCD 196
            :.||....|.|.::| |||..||||.|..::..::.:||..::.||..||:.||| |.:||.:||
 Worm    69 SWGQLMSVGGLGMFK-ICPIFKGVGIAAAVMAFWLNIYYIVVLSWAATYLYNSFTMSDVPWKNCD 132

  Fly   197 NPWNTENCMQ---------------------VTSENFTEL---------------------ATSP 219
            :.|||.||..                     :|.::..|.                     ..||
 Worm   133 HAWNTPNCRSEYVKIPCDSNRTIAEFFNVKVLTHDHIHEYKKQFFVGEKMNWTVCSAADLSVVSP 197

  Fly   220 AKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVL 284
            .|||:..:||..  .:||:..|.::..|||.:..|:::.|..::|||:..||||::||..||::|
 Worm   198 VKEFWNHRVLGI--SSGLENPGGIRWDLALFLLLVWIICYLCIFKGVKWTGKVVYITASFPYMML 260

  Fly   285 IILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNC 349
            ..||:||::|.||..|:::||.|::.||..||||:||.:|:|||.|.|.|.|:||.||||||||.
 Worm   261 FCLLIRGLTLEGAGVGLEFYLKPDFSKLLESKVWVDAVTQVFFSYGLGLGALVALGSYNKFNNNV 325

  Fly   350 YRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLVFIVYPEAIATMSGSVFW 414
            |:.||....:|..||..|||||||.:|:||..|:.|:.:|...||||:|:.||..|..:..:.||
 Worm   326 YKQALTVCFVNSGTSVFAGFVIFSFIGFMATQQEKSVAEVAQAGPGLLFLAYPSGILQLPYTQFW 390

  Fly   415 SIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRR--RELFVLLLLAFIFLCALPTMTYGGV 477
            |.:||||::.||:||.|..:|...||:.||:|::..::  ||:||.::....:|..|.|:|.||.
 Worm   391 SCLFFLMVLFLGVDSQFCTMEGFFTAIIDEFPQIRRKKYGREIFVGVICVISYLIGLTTVTEGGF 455

  Fly   478 VLVNFLNVY-GPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLL 541
            .:....:.| ..|.|:|:::|.|...:.|..|:||:...::.|:|..|..:|:.||.:.:|....
 Worm   456 YVFQLFDFYAASGWALLWLLFFECIAISWSLGIDRWYEHMKSMIGYYPSAWWKFCWVFATPSVCF 520

  Fly   542 TIFIFSIMGYKEML--GEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGCRQRLQESF 604
            .:.:|.::.|:.:.  ...|.||.|.:..||.::.||:||||.|.|: .:|.:.|..:::::...
 Worm   521 GVLLFGLIKYQPLRIDAYNYDYPVWGHIFGWFLSLSSMLCIPGYAIW-IWFKTPGTVQEKIKLLC 584

  Fly   605 QPE 607
            :|:
 Worm   585 RPD 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	225/580 (39%)
snf-11	NP_505873.2	SLC6sbd-TauT-like	10..586	CDD:271387	225/579 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820