Protein Alignment SerT and snf-10

DIOPT Version :10

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_505682.2
• Gene: snf-10 / 191769
• WormBaseID: WBGene00004909
• Length: 673
• Species: Caenorhabditis elegans
• Alignment Length: 690
• Identity: 171/690 - (24%)
• Similarity: 289/690 - (41%)
• Gaps: 108/690 - (15%)

  Fly     4 SGSSDFAGAAATTGRSNPAPWSDDKESPNNEDDSNEDDGDHTTPAKVTDPLAPKLANNERILVVS 68
            :.||||.....|..:|.....|...|:.|  ||:.....:...|.|.|.. |..::|   |...|
 Worm     2 ASSSDFKQLKQTRTKSEETTRSASNETVN--DDNRSTTTEEIIPIKKTSN-ATAISN---IGFKS 60

  Fly    69 VTERTRE-----------TWGQKAEFLLAVIGFAVDLGNVWRFPYIC-YQNGGGAFLVPYCLFLI 121
            ||....|           ||..|.|.:.|.:.|....||:|.|||:| |..|...:...:|  .:
 Worm    61 VTNLALENIGLDTKMEGPTWTSKWEAITATLSFVTCSGNIWFFPYLCGYYGGWFPYQFTFC--YV 123

  Fly   122 FGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTI--IGWAVY---- 180
            |..:||.|:|.||||:.....||::.|:.||:.|:...:|.|     |.:.||  ..||:|
 Worm   124 FIAVPLLYLETALGQYASASPLSVFSRMAPAMAGLSAGMCFI-----MVFRTISLSVWAIYDLTI 183

  Fly   181 --YLFASFTSKLPWTSCDNPWNTENCMQV-TSENFTELATSPAKEFFE-RKVLESYKG------- 234
              :...|..|..||.||....:.:.|:.. .|...|.:.....||..| :::|.:.:|
 Worm   184 FTHASQSIWSTSPWESCQESQSGDYCVNYKLSSKCTWIQPGSDKECDEYQEMLIATRGFQQRKSP 248

  Fly   235 -----NGLDF--------MGPVKPTLALCVFGVFVLVYFSLWKGVRSAG--KVVWVTALAPYVVL 284
                 :||.:        ..|...|..:|...:::::      |:.|.|  ||:..|.:....:|
 Worm   249 FMSFVHGLMYKRSITMNDWEPPSVTSIICAVCLWIII------GIISIGGSKVLGRTGIVALTLL 307

  Fly   285 ----IILLVRGVSLPGADEGI-KYYLTPEWHKLKNSKV--WIDAASQIFFSLGPGFGTLLALSSY 342
                |:||..|:||....... .::...|.::.|...|  |.|||:....:|..|.|.:...:|.
 Worm   308 LVGTIMLLSYGMSLNDTTNVFTAFFYQSEGYEDKWMWVWSWADAAAHALRALNVGCGGIQKFASL 372

  Fly   343 NKFNNNCYRDALITSSIN---CLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEG-PGLVFIVYPE 403
            |.|:|..:||.|:.|.::   .:.:.|..|:..:.:|.:.|....:.:::.|.. |.::..|..|
 Worm   373 NNFHNKIHRDVLLISIVSFVFYICTGLLSFMFMAEIGRLYYPDLEASERIQLYATPVMIESVISE 437

  Fly   404 AIATMSGSVFWSIIFFLMLITL---GLDSTFGGLEAMITALCDEYPRVIGR------RRELFVLL 459
            .:...|....|..:|:|.|...   |:.|....:.:||....:...|..|:      :|.:.:.:
 Worm   438 ILTNSSMGSIWVFLFWLTLAACSIQGISSYIWVISSMIVERLNGSRRKYGKALASWHKRAIILAI 502

  Fly   460 LLAFIFLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLG--S 522
            :.....:.:||.:..||:.|::.:..:. ....:|:.|||...|.:.||..|||.::..|:|  .
 Worm   503 MSVTGLISSLPFLGNGGINLMSSIETFA-SYGTIFIAFVEVITVSYVYGFKRFSVNIRAMIGGHG 566

  Fly   523 KPGLFWRICWTYISPVFLLTIF--IFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYII 585
            .|.:||.:.|..|||:.|:..|  |.:..|.|:...|.....|   .:|:     |:|.:|...:
 Worm   567 PPNVFWWLNWLVISPILLIVTFGCIVATFGQKKAFNENSIVSD---PIGY-----SLLVMPCIFV 623

  Fly   586 YKFFFASKGGCRQRLQE------------SFQPEDNCGSV 613
            ..:|...:...|:.::.            ...|||...:|
 Worm   624 ILYFLRDEYDRRKNMEPFVVMIRATGDWGPMNPEDRRNAV 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	147/612 (24%)
snf-10	NP_505682.2	SNF	78..628	CDD:395155	144/571 (25%)