Protein Alignment SerT and snf-12

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_509527.1
• Gene: snf-12 / 181143
• WormBaseID: WBGene00004911
• Length: 1022
• Species: Caenorhabditis elegans
• Alignment Length: 745
• Identity: 207/745 - (27%)
• Similarity: 360/745 - (48%)
• Gaps: 101/745 - (13%)

  Fly    74 RETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFH 138
            ||.|..:.:|.|:.:||.|.:|:..|||...||:|||.|.:||...|||.||||.::.|:|||:.
 Worm   157 RELWRTQKDFFLSCLGFMVGVGHTMRFPAKVYQHGGGVFFIPYLFSLIFFGLPLVFLHLSLGQYT 221

  Fly   139 RCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFAS-----FTSKLPWTSCDNP 198
            .....:.::|:.|...|||:|:.:|.|.:.:|||.|:.||::|.|.|     ...:|||.:|.:.
 Worm   222 GQAANTAFQRLMPIGSGVGWALVVIAIPVAVYYNIIVAWAIHYFFQSAKGLLLGDELPWETCRDE 286

  Fly   199 WNTEN-CMQV----TSENFTELATSPAKEFFERKVLESYKGNGLDF-MGPVKPTLALCVFGVFVL 257
            |..:| |..:    :..|.|...|:| :.||..:|| |....| || :||::..|.|.:...::|
 Worm   287 WQLDNRCCNLHNLHSCFNSTNSITAP-EAFFHSEVL-SLSTFG-DFALGPLQSHLVLSLAAAWLL 348

  Fly   258 VYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAA 322
            |:|.::||:.|..:.:.|||..||::|.|||:||:|||||::|:.:..|.:..||...::|..||
 Worm   349 VFFGVFKGLGSIAQTMNVTATVPYLLLSILLLRGISLPGANKGLTFLFTVDSTKLWKWQIWKSAA 413

  Fly   323 SQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSID 387
            .|:|:.||...|.|:::::::::.||.|||:::...::.|||.|:|.||||.:|::|....::::
 Worm   414 EQVFYELGIDAGPLISMAAFSRYRNNIYRDSVLLVIMDALTSCLSGMVIFSFVGFIASESNSNVN 478

  Fly   388 KVGLEGP-GLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYP---RV 448
            .|....| .|.|.|||...:.|.....|:.:||.||:...:|:.|..||.:.:|..:.:.   :.
 Worm   479 DVLKHDPLYLSFTVYPGVTSFMYWGGLWATLFFGMLVLAAIDAEFAWLEMIASAFMNHFSMKNKA 543

  Fly   449 IGRRRELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFS 513
            :..|  |...|.||..|| .||....||:.:.:.:...........:..:..|.|.:.||:|.:.
 Worm   544 VENR--LLAFLCLAGFFL-GLPLCAQGGIFVFHAIENLNANWNSFSLALLSVAIVCYVYGIDNYL 605

  Fly   514 SDVEQMLG------SKP--------------GLFWRICWTYISPVFLLTIFIFSIMGYKEMLGEE 558
            :|:..||.      ||.              |::.:....:|.||.|..:.:.|::||:.:....
 Worm   606 TDISAMLRVPRIQISKATRLKEKLIYFFGPGGIYIKFSLCFICPVILTVLLVASVLGYQRISFAG 670

  Fly   559 YYYP-DWSYQVGWAVTCSSVLCIPMY-------------IIYKFFFASKGGCRQRLQESFQPED- 608
            ...| |:.. |.|.|....:|.:|:.             ::...|..|:  .|:...:|.:|:|
 Worm   671 RPIPIDYEI-VAWIVMIGPLLVVPLVAFMQIRQIRNEGKLLKSLFDTSE--WRESQDDSLEPKDL 732

  Fly   609 ---NCGSV--VPGQQGTSVXHDHAQ---VHVNIRTSCTSIKIYNLNCSSNSNSLSPTTSGAEGRS 665
               ..|..  .|.::.|.....|.:   ::::.|......:::.|..     ||.|
 Worm   733 YMRQSGKFESPPNRRRTPTIFTHRENTYMYIDSRGPTVRSRVFPLGA-----SLDP--------- 783

  Fly   666 CYSTNLNCNHSCPSEDQYRSRNHQQQQQQHHHHHHHQHQHRISSDIISSSLRQSHSHSLSLCSVQ 730
             |.....           |.|:.|||.::...::..:.....:| .::|:::  |:..:.|....
 Worm   784 -YGWKAG-----------RLRDRQQQIEETASNYSEEDSATTNS-FMASTVK--HNDDMELTLFG 833

  Fly   731 SNPMATTRIPLAAEDNNCSLRLSSCQPLKF 760
            |.|..     |..::...:.|.|...|:.:
 Worm   834 SPPAI-----LGDDEKIMTTRFSESMPVNY 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	180/581 (31%)
snf-12	NP_509527.1	SLC6sbd	158..660	CDD:271359	165/507 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820