Protein Alignment SerT and snf-7

DIOPT Version :10

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_499702.2
• Gene: snf-7 / 176723
• WormBaseID: WBGene00004906
• Length: 705
• Species: Caenorhabditis elegans
• Alignment Length: 659
• Identity: 188/659 - (28%)
• Similarity: 295/659 - (44%)
• Gaps: 125/659 - (18%)

  Fly    15 TTGRSNP------APWSDDKESPNNEDDSNEDDGDHTTPAKVTDPLAP----------KLANNER 63
            |||.|.|      ||.:..|                 |.|....|:.|          :.|...:
 Worm    11 TTGSSAPSVIPPTAPTASVK-----------------TKAPTKGPVQPQKKPTTVDNGRRAYRNQ 58

  Fly    64 ILVVSVTERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLF 128
            ::|.:|   .|:.: :..|..|:.:|.||.|||:||||...|:|||.:||:.|.:..|...:|..
 Worm    59 VVVENV---DRQAF-RGIESFLSSLGQAVGLGNIWRFPTTAYKNGGLSFLIAYVVCGILFAVPAI 119

  Fly   129 YMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLF-ASFTSKLPW 192
            :||.||||:......:.::|:.|.|:|||:..||:...:|:||..:|.|.|.||| ..:.:|:
 Worm   120 HMEFALGQYAAKSPPAAFRRMMPILEGVGWMTCLVGAIIGVYYMIVISWIVLYLFNIIYATKI-- 182

  Fly   193 TSCDNPWNTEN---CMQ---------------VTSENFTELATSPAK------------------ 221
            :.|:|.||...   |.:               :...|.|..|:..:|
 Worm   183 SKCNNDWNKNRSTICYEGVKQKLCSGYMLNSSLVMTNLTRNASVHSKMMYIDGKCQNATNMKLAV 247

  Fly   222 ---EFFERKVLESYKG----NGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALA 279
               :||...|::...|    |.::.  |:...:|:|    :|:...||.:|:::.||:.:.|.|.
 Worm   248 GTEQFFTNFVVKPSTGFTDFNSINV--PMLAAVAVC----WVIAIISLIRGMKAIGKLSYYTVLL 306

  Fly   280 PYVVLIILLVRGVSLPGADEGIKYYLTPEWHK-----------LKNSKVWIDAASQIFFSLGPGF 333
            ||.::|.|::||::|.||..|:.:..   |.|           |.:..|||.|..|:.|||..|.
 Worm   307 PYAIIIALMIRGLTLEGASTGLHFLF---WGKPNEYGHYDFAGLYDPDVWIAALMQMCFSLSIGQ 368

  Fly   334 GTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSI------DKVGLE 392
            |.|:.:.||||...|.||||.:....:.|.|.|.|..:||.||::|..:..||      ::|..|
 Worm   369 GGLMNIGSYNKKTYNWYRDAYLVVLCDTLMSLLGGTAVFSTLGFLAEQRNISISNPKGFNEVVQE 433

  Fly   393 GPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFV 457
            |..|.||||.||||.|.....|..:||:||..||:.:....:|.:.:.|.|.: ..:.:.|.:.|
 Worm   434 GHALAFIVYTEAIAQMPYPFLWYALFFVMLFLLGISTEIVIIETVCSCLADRF-HYLRQHRWITV 497

  Fly   458 LLLLAFIFLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQM--- 519
            :.:....||..|...:..|....:..:.|..|::......:....|.|.||:|.|.:|:.:|
 Worm   498 VTVSTTFFLLGLVMTSDAGFYWFDLYDEYSAGVSATIGTAIMCLTVCWCYGLDNFRADIREMWEE 562

  Fly   520 --------LGSKPGLF-WRICWTYISPVFLLTIFIFSIMGYK-EMLGEEYYYPDWSYQVGWAVTC 574
                    ||  ||.: |.|.|.:::|:..|.|....|...| ...|:...||......||.|..
 Worm   563 PESRLDKYLG--PGAYVWTIVWRFVTPICCLVIMFAWIWDKKYPFKGDSKKYPPVFDAFGWFVAA 625

  Fly   575 SSVLCIPMY 583
            .....:|::
 Worm   626 LPFFVVPVF 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	173/584 (30%)
snf-7	NP_499702.2	SLC6sbd	70..598	CDD:271359	163/541 (30%)