Protein Alignment SerT and dat-1

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_499043.1
• Gene: dat-1 / 176304
• WormBaseID: WBGene00000934
• Length: 615
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 257/553 - (46%)
• Similarity: 364/553 - (65%)
• Gaps: 21/553 - (3%)

  Fly    74 RETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFH 138
            ||.|..|.:|||:|:||||||||:|||||:|::||||.||:||.:.::..|:|||||||.|||::
 Worm    40 REQWSGKLDFLLSVVGFAVDLGNIWRFPYLCFKNGGGVFLIPYSIMVLLTGVPLFYMELCLGQYY 104

  Fly   139 RCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTEN 203
            |.|.::.|.||||..||:||.:.|...|:..:||.|:.|.::||:.||:..|||.||:|.:|:..
 Worm   105 RKGAITTWGRICPLFKGIGYCVILTAFYVDFFYNVILAWGLHYLYTSFSFNLPWASCNNSYNSPA 169

  Fly   204 CMQV-TSENFTELA-----------TSPAKEFFERKVLESYKGN--------GLDFMGPVKPTLA 248
            |.:. .||:.|.:.           .|.|:|:|.:..|..::.|        .:..:|.|:..:|
 Worm   170 CYEPHWSEDGTAMCRSANQSVSAEKISAAEEYFYKGFLGLHEANAPNSHVIRSVTDLGNVRWDIA 234

  Fly   249 LCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLK 313
            |.:|.|:::.|||:|||:.::|||||.|||.|||||.||.:|||:|||...||:|||.|.:..||
 Worm   235 LSLFVVYLICYFSMWKGIHTSGKVVWFTALFPYVVLGILFIRGVTLPGWQNGIEYYLRPNFEMLK 299

  Fly   314 NSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYM 378
            ...||.|||:|:|||||||||.|:|.||||.|:||.|.|||.||.|||.||||:|||||||||||
 Worm   300 RPSVWQDAATQVFFSLGPGFGVLMAYSSYNDFHNNVYVDALFTSFINCATSFLSGFVIFSVLGYM 364

  Fly   379 AYVQKTSIDKVGLEGPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCD 443
            :......|:.|..|||||||:|||||::||..:.|||::|||||:||||||:|||.||:||.|.|
 Worm   365 SCKSGKPIEAVAQEGPGLVFVVYPEALSTMPYAPFWSVLFFLMLMTLGLDSSFGGSEAIITGLSD 429

  Fly   444 EYPRVIGRRRELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYG 508
            |:| ::.:.||:||..|.||..:..:...|.||::::.:|.:||....:|..||.||..:.:.||
 Worm   430 EFP-ILKKNREVFVGCLFAFYMVIGIAMCTEGGILIMEWLIIYGTTWGLLIAVFCEAMVIAYIYG 493

  Fly   509 VDRFSSDVEQMLGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVT 573
            :.:|..||::|:|.:||.:|:.||:..:|..||::...:.:.|:.:..::|.||..:..:|....
 Worm   494 LRQFVHDVKEMMGFRPGNYWKFCWSCAAPFILLSMITSNFINYQALTYQDYTYPTAANVIGIIFA 558

  Fly   574 CSSVLCIPMYIIYKFFFASKGGCRQRLQESFQP 606
            .|....||:..||||..|......::.|....|
 Worm   559 LSGASFIPLVGIYKFVNARGNTISEKWQRVTMP 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	257/553 (46%)
dat-1	NP_499043.1	SLC6sbd_SERT-like_u1	40..591	CDD:271405	256/551 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53371
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	1	1.000	-	-		FOG0000975
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101590
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X639
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.730