Protein Alignment SerT and snf-3

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_493910.2
• Gene: snf-3 / 173493
• WormBaseID: WBGene00004902
• Length: 600
• Species: Caenorhabditis elegans
• Alignment Length: 543
• Identity: 200/543 - (36%)
• Similarity: 314/543 - (57%)
• Gaps: 30/543 - (5%)

  Fly    71 ERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALG 135
            |..|..|..|.:||::::.:||.|||||||||:||:||||:|||.|.:|.....:|:|.||:.:|
 Worm    27 EPDRGQWTGKFDFLMSMVAYAVGLGNVWRFPYLCYKNGGGSFLVVYMIFFCLAAVPIFLMEVTVG 91

  Fly   136 QFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWN 200
            |:.:.|.:.:| .:||..:|||....:|......|:..|:.||::|:.:|.....||.:|:|.||
 Worm    92 QYLQKGAMEMW-LMCPLFRGVGIGNVVIAFMCIAYFCVIVAWAMFYMISSIAWVFPWETCNNYWN 155

  Fly   201 TENCMQVTSENFTELATSPA-------------KEFFERKVLESYKGNGLDFMGPVKPTLALCVF 252
            ...|: ...|||||||...|             ::|:|::||.. .|:..:| |.::..|...:.
 Worm   156 DATCV-TGKENFTELARIKALVASAGGHTQTSVEQFWEKRVLHD-TGDISEF-GGIQWELFFIMA 217

  Fly   253 GVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKV 317
            ..:::|||:||||:..|.|.|:..||.|||::.|||:||::|.||..||.:||.|...:|.::.|
 Worm   218 AAWLIVYFALWKGITQARKFVYFCALFPYVLIFILLIRGLTLEGAGTGIYFYLKPNATRLLDTAV 282

  Fly   318 WIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQ 382
            |.||.:|:|:|.|.|||.|:||.|:||||:||::||:....||..||..|||.:||:||||::|.
 Worm   283 WKDAGTQVFYSYGVGFGALIALGSHNKFNHNCFKDAITMCFINGCTSITAGFAVFSILGYMSHVA 347

  Fly   383 KTSIDKVGLEGPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPR 447
            :..|.::...|.||.|:.|||..:.:.....::::||||:..|||||....:|.:.|||.|.:|
 Worm   348 QKDISEIVKPGVGLAFLAYPEVASNLPMKQVFAVLFFLMITILGLDSQVCMMEGLFTALEDAFP- 411

  Fly   448 VIGRRRELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVYG-PGLAILFVVFVEAAGVFWFYGVDR 511
            ::.:.::..:.:...|.|...:|.:|:.|...:...:.|| .|.|:|||||.|..|:.:.:|...
 Worm   412 ILRKYKKQSLGIFCLFFFCIGIPMVTHSGSHWLTLFDAYGASGYALLFVVFFEVVGLAYGFGAHN 476

  Fly   512 FSSDVEQMLGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPD------WSYQVGW 570
            ....:.:|:|..........|.:.:|...|.:|:|.::.|..:     .|||      |:...||
 Worm   477 IRKALHEMIGVTLPKGIEYVWKFCAPATSLVLFVFCVVYYHPV-----KYPDGKDFPFWANAFGW 536

  Fly   571 AVTCSSVLCIPMYIIYKFFFASK 593
            .::..|::.||.|.||..||.:|
 Worm   537 FLSSCSMVVIPGYAIYYLFFTNK 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	199/540 (37%)
snf-3	NP_493910.2	SLC6sbd-TauT-like	30..571	CDD:271387	199/540 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820