Protein Alignment SerT and mod-5

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_491095.3
• Gene: mod-5 / 171879
• WormBaseID: WBGene00003387
• Length: 671
• Species: Caenorhabditis elegans
• Alignment Length: 614
• Identity: 298/614 - (48%)
• Similarity: 406/614 - (66%)
• Gaps: 35/614 - (5%)

  Fly    30 SPNNEDDSNEDDGDHTTPAKVTDPLAPKLANNERILVVSVTERT---RETWGQKAEFLLAVIGFA 91
            |.::..|.||       |......|.|.....    |.::..|:   |:.|..|.||||||:|:|
 Worm    64 STSHSIDPNE-------PIAALGGLTPTKEGR----VAALRRRSSMVRDKWATKMEFLLAVVGYA 117

  Fly    92 VDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGV 156
            |||||:||||.:||::||||||:||.:.|:.||||:|||||.||||||.||:|||:::||..:|:
 Worm   118 VDLGNIWRFPSVCYKHGGGAFLIPYFIMLMIGGLPMFYMELVLGQFHRSGCVSIWRKVCPLFRGI 182

  Fly   157 GYAICLIDIYMGMYYNTIIGWAVYYLFASFT----SKLPWTSCDNPWNTENC---MQVT-SENFT 213
            ||.||.|..::.::||.||..|||:...|.:    |::||.||.|||||..|   :.|| |.|.|
 Worm   183 GYGICCICTFIAIFYNAIIAQAVYFAIVSLSKIWDSEVPWASCGNPWNTPRCSDDLNVTISRNGT 247

  Fly   214 ELATSPAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTAL 278
            .| |:|::|::..||||..|..|.|.:|.||.::|:|:..||::|||:||||.:|:||:|||||.
 Worm   248 PL-TTPSEEYYLYKVLEVQKSTGFDDLGGVKTSMAVCLLAVFIMVYFALWKGPQSSGKIVWVTAT 311

  Fly   279 APYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALSSYN 343
            |||::|.|||:||:.||||..|:.||:||::.|||:..||..||:|||||||||||.||||||||
 Worm   312 APYIILSILLIRGLLLPGAKNGLYYYVTPDFEKLKDPAVWSAAATQIFFSLGPGFGVLLALSSYN 376

  Fly   344 KFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDK-VGLEGPGLVFIVYPEAIAT 407
            .|||||||||:.||.|||.|||.:|.|:||.||||:.:....|:: ||.....|:|||||:|:||
 Worm   377 DFNNNCYRDAVTTSIINCATSFFSGCVVFSTLGYMSLLTNKPINEVVGEHDASLIFIVYPQALAT 441

  Fly   408 MSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAFIFLCALPTM 472
            |..|.|||.|||:||||||:||||.|:||.||..||| .|.:.:.|:.|||::....:..:.|.:
 Worm   442 MDYSCFWSFIFFVMLITLGIDSTFAGIEAFITGFCDE-SRFLSKNRKWFVLVICIIYYFLSFPAI 505

  Fly   473 TYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISP 537
            :|||..::.||:.||..|::||:|..|...|.||||||:||.|:..|||..||::||:||| .||
 Worm   506 SYGGQFVIPFLDEYGVSLSVLFIVTCEMIAVCWFYGVDQFSKDIRAMLGFYPGIYWRVCWT-CSP 569

  Fly   538 VFLLTIFIFSI--MGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGCRQRL 600
            ||:..|||.::  ..:|.:....|.:|.||..:||.:...|||.||::.|. :..:..|...:|.
 Worm   570 VFISVIFIMTVYNSSFKPIQMASYTFPWWSVILGWFLRLLSVLAIPVFAII-YLLSGTGTLYERF 633

  Fly   601 QESFQPEDNCGSVVPGQQGTSVXHDHAQV 629
            :.:..|:....|      .||:..|..|:
 Worm   634 RWAITPQQRRNS------ATSLAADPTQI 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	283/543 (52%)
mod-5	NP_491095.3	SLC6sbd_SERT-like	100..639	CDD:271388	283/542 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	591	1.000	Domainoid score	I101
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H99955
Inparanoid	1	1.050	594	1.000	Inparanoid score	I527
Isobase	1	0.950	-	0	Normalized mean entropy	S2944
OMA	1	1.010	-	-		QHG53371
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	1	1.000	-	-		FOG0000975
OrthoInspector	1	1.000	-	-		oto19424
orthoMCL	1	0.900	-	-		OOG6_101590
Panther	1	1.100	-	-	LDO	PTHR11616
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4270
SonicParanoid	1	1.000	-	-		X639
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.820