Protein Alignment SerT and Slc6a9

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_001342104.1
• Gene: Slc6a9 / 14664
• MGIID: 95760
• Length: 652
• Species: Mus musculus
• Alignment Length: 600
• Identity: 245/600 - (40%)
• Similarity: 356/600 - (59%)
• Gaps: 42/600 - (7%)

  Fly    44 HTTPAKVTDPLAPKLANNERILVVSVTER----TRETWGQKAEFLLAVIGFAVDLGNVWRFPYIC 104
            |...|....|:|.........:....|::    ||..||.:.||:|..:|:||.|||||||||:|
Mouse    12 HPGMASAQGPVATPSPEQNGAVPSEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLC 76

  Fly   105 YQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGM 169
            |:||||||:.||.:.|||.|:|||:|||:.|||...|||.:| ||.|..|||||.:.::..|:|:
Mouse    77 YRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGI 140

  Fly   170 YYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTENCMQVTSE--------------------NFTE 214
            |||.:|..|.||.|:|.|..|||..|:|||||.:|..|...                    |:|.
Mouse   141 YYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTPDCAGVLDASNLTNGSRPAALSGNLSHLFNYTL 205

  Fly   215 LATSPAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALA 279
            ..|||::|::...||:  ..:.:...|.|:..|..|:...:|:|:..|.:||:|:||||:.||..
Mouse   206 QRTSPSEEYWRLYVLK--LSDDIGNFGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTATF 268

  Fly   280 PYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNK 344
            |||||.||.||||:|.||..||.|||||:|.|:..:|||.|||||||:|||..:|.|:.::||||
Mouse   269 PYVVLTILFVRGVTLEGAFTGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNK 333

  Fly   345 FNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLVFIVYPEAIATMS 409
            |:||||||::|.|..||.||..|||||||:||:||......:.:|...||||.|:.||||:..:.
Mouse   334 FHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLP 398

  Fly   410 GSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAFI-FLCALPTMT 473
            .|..||::||.|||.|||.:.|..||.::||:.||.......:::.:|.|.:|.. ||..:|..:
Mouse   399 ISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTS 463

  Fly   474 YGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPV 538
            ..|:..:..::.|....:::.:..:....:.:.||...:..|::.|||..|.||::|||.::||.
Mouse   464 QAGIYWLLLMDNYAASFSLVVISCIMCVSIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPA 528

  Fly   539 FLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGCR------ 597
            .:..|.||:::.|:.:....|.||.|:..:|:.:..|||:|||:|.:::.       ||
Mouse   529 IIFFILIFTVIQYRPITYNHYQYPGWAVAIGFLMALSSVICIPLYALFQL-------CRTDGDTL 586

  Fly   598 -QRLQESFQPEDNCG 611
             |||:.:.:|..:.|
Mouse   587 LQRLKNATKPSRDWG 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	237/560 (42%)
Slc6a9	NP_001342104.1	SLC6sbd_GlyT1	30..613	CDD:212067	240/581 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820