Protein Alignment SerT and Slc6a9

DIOPT Version :10

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_006238687.1
• Gene: Slc6a9 / 116509
• RGDID: 621243
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 567
• Identity: 242/567 - (42%)
• Similarity: 348/567 - (61%)
• Gaps: 38/567 - (6%)

  Fly    73 TRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQF 137
            ||..||.:.||:|..:|:||.|||||||||:||:||||||:.||.:.|:|.|:|||:|||:.|||
  Rat    31 TRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLVFCGIPLFFMELSFGQF 95

  Fly   138 HRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTE 202
            ...|||.:| ||.|..|||||.:.::..|:|:|||.:|..|.||.|:|.|..|||..|:|||||.
  Rat    96 ASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTP 159

  Fly   203 NCMQVTSE--------------------NFTELATSPAKEFFERKVLESYKGNGLDFMGPVKPTL 247
            :|..|...                    |:|...|||::|::...||:.....| || |.|:..|
  Rat   160 DCAGVLDASNLTNGSRPTALSGNLSHLFNYTLQRTSPSEEYWRLYVLKLSDDIG-DF-GEVRLPL 222

  Fly   248 ALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKL 312
            ..|:...:|:|:..|.:||:|:||||:.||..|||||.||.||||:|.||..||.|||||:|.|:
  Rat   223 LGCLGVSWVVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFTGIMYYLTPKWDKI 287

  Fly   313 KNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGY 377
            ..:|||.|||||||:|||..:|.|:.::|||||:||||||::|.|..||.||..|||||||:||:
  Rat   288 LEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGF 352

  Fly   378 MAYVQKTSIDKVGLEGPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALC 442
            ||......:.:|...||||.|:.||||:..:..|..||::||.|||.|||.:.|..||.::||:.
  Rat   353 MANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIV 417

  Fly   443 DEYPRVIGRRRELFVLLLLAFI-FLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWF 506
            ||.......:::.:|.|.:|.. ||..:|..:..|:..:..::.|....:::.:..:....:.:.
  Rat   418 DEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVSIMYI 482

  Fly   507 YGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWA 571
            ||...:..|::.|||..|.||::|||.::||..:..|.||:::.|:.:....|.||.|:..:|:.
  Rat   483 YGHRNYFQDIQMMLGFPPPLFFQICWRFVSPTIIFFILIFTVIQYRPITYNHYQYPGWAVAIGFL 547

  Fly   572 VTCSSVLCIPMYIIYKFFFASKGGCR-------QRLQESFQPEDNCG 611
            :..|||:|||:|.:::.       ||       |||:.:.:|..:.|
  Rat   548 MALSSVICIPLYALFQL-------CRTDGDTLLQRLKNATKPSRDWG 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	239/560 (43%)
Slc6a9	XP_006238687.1	SLC6sbd_GlyT1	16..599	CDD:212067	242/567 (43%)