Protein Alignment SerT and slc6a12

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_031754510.1
• Gene: slc6a12 / 100492029
• XenbaseID: XB-GENE-6033368
• Length: 612
• Species: Xenopus tropicalis
• Alignment Length: 595
• Identity: 260/595 - (43%)
• Similarity: 369/595 - (62%)
• Gaps: 37/595 - (6%)

  Fly    24 WSDDKESPNNEDDSNE----DDGDHTTPAKVTDPLAPKLANNERILVVSVTERTRETWGQKAEFL 84
            |.|.::..|....|:.    .:|.|..| ::.|                     |..|..|.||:
 Frog     3 WKDCEKPRNGAGGSDTLCALGEGRHREP-EIED---------------------RGQWSNKVEFV 45

  Fly    85 LAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRI 149
            |:|.|..:.|||||||||:||:||||||.:||.:||...|:|:|::|.||||:...|.::.|::|
 Frog    46 LSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTSQGGITAWRKI 110

  Fly   150 CPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTENCMQVT--SENF 212
            ||..:|:|||..:|:.|:.:||..|:.||::|||:|||::|||.:|:|.||||:|:...  ||||
 Frog   111 CPLFEGIGYASQVIEGYLNIYYIVILAWALFYLFSSFTAELPWATCNNTWNTEHCIDFVGKSENF 175

  Fly   213 TEL--ATSPAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWV 275
            |.|  :||...||:||:||  :...|::.:|.|:..||||:...:::.||.:||||:|.||||:.
 Frog   176 TSLENSTSSVVEFWERRVL--HLSEGIEHLGNVRWDLALCLLLAWIICYFCIWKGVKSTGKVVYF 238

  Fly   276 TALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALS 340
            ||..|||:|||||||||:||||.|||.:||.|:..:|::.:||:||.:|||||.....|.|.||.
 Frog   239 TATFPYVMLIILLVRGVTLPGAYEGIIFYLKPDMTRLQDPQVWMDAGTQIFFSYAICQGCLTALG 303

  Fly   341 SYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLVFIVYPEAI 405
            ||||:|||||||.:....:|.:|||:|||.||||||:||..|...|.:|...||||.||.||:|:
 Frog   304 SYNKYNNNCYRDCIALCFLNSITSFVAGFAIFSVLGFMAQEQGVPISEVAESGPGLAFIAYPKAV 368

  Fly   406 ATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGR--RRELFVLLLLAFIFLCA 468
            ..|..|..||.:||||||.|||||.|..:|:::||:.|.:|.|..:  |||.|:|.:....:|..
 Frog   369 TMMPVSPLWSCLFFLMLIFLGLDSQFVCVESLVTAIVDMFPHVFRKKYRREFFILAVAVICYLLG 433

  Fly   469 LPTMTYGGVVLVNFLNVY-GPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICW 532
            |..:|.||:.:....:.| ..|..:|||...|...|.:.||.:||..::|.|:|.:|....:.||
 Frog   434 LILLTEGGMYVFQLFDYYAASGTCLLFVAIFEVICVGYVYGANRFYDNIEDMIGYRPWPLVKYCW 498

  Fly   533 TYISPVFLLTIFIFSIMGYKEM-LGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGC 596
            .:.:|...|..|:||::.|..: ....|.||.|.|.:||.:..||::|||:|..| ....:||..
 Frog   499 LFATPAVCLGTFLFSLIKYSPLKYNNRYVYPSWGYAIGWLMALSSMICIPIYAFY-IILRTKGSF 562

  Fly   597 RQRLQESFQP 606
            .|||::...|
 Frog   563 TQRLKQLVTP 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	252/541 (47%)
slc6a12	XP_031754510.1	SLC5-6-like_sbd	34..572	CDD:382020	252/561 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010