Protein Alignment SerT and slc6a7

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_002940131.3
• Gene: slc6a7 / 100487063
• XenbaseID: XB-GENE-479449
• Length: 634
• Species: Xenopus tropicalis
• Alignment Length: 620
• Identity: 247/620 - (39%)
• Similarity: 358/620 - (57%)
• Gaps: 45/620 - (7%)

  Fly    30 SPNNEDDSNEDDGDHTTPAKVTDPLAPKLANNERILVVSVTERTRETWGQKAEFLLAVIGFAVDL 94
            ||::.||:..|         :..|                  ..|..|..|.:|||:.||:.|.|
 Frog    20 SPSDRDDTELD---------IEYP------------------EDRGNWSGKLDFLLSCIGYCVGL 57

  Fly    95 GNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYA 159
            ||||||||..|.|||||||:||.:.|...|:|||:|||:||||...|.|::|| |.|..||||..
 Frog    58 GNVWRFPYRAYTNGGGAFLIPYFIMLAICGIPLFFMELSLGQFSSLGPLAVWK-ISPLFKGVGMG 121

  Fly   160 ICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTENCMQ---VTSENFTEL-----A 216
            :.||...:.:|||.||.:.::|||||.||.|||..|.|.|||:.|:.   :.:.|...|     .
 Frog   122 MLLIVALVAIYYNMIIAYVLFYLFASLTSSLPWEHCGNWWNTDLCLDHHVIRASNSALLVNISNT 186

  Fly   217 TSPAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPY 281
            .||::|::.|.||.....:|:...|.::..|.||:...:.:||..:.|||:|:||||:.||..||
 Frog   187 VSPSEEYWSRYVLHIQGSSGIGDPGQLRWKLCLCLLLSWTIVYLCILKGVKSSGKVVYFTATFPY 251

  Fly   282 VVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFN 346
            ::|::||:|||:|.||..|||:||||::..|..|||||:||.|||:|||.|||.||..:|||.|:
 Frog   252 IILVMLLIRGVTLEGAWIGIKFYLTPQFEHLLTSKVWIEAALQIFYSLGVGFGGLLTFASYNTFH 316

  Fly   347 NNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLVFIVYPEAIATMSGS 411
            .|.|||..|.:..|..||.||||.||||||||:......:|:|...||||.|:|||:|:..:..|
 Frog   317 QNIYRDTFIVTLGNAFTSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLS 381

  Fly   412 VFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAFIFLCALPTMTYGG 476
            .|||.:||.||:||||||.|..:|.::||:.||:|..:..::.:|..::...:||..|...|.||
 Frog   382 PFWSFLFFFMLLTLGLDSQFAFMETIVTAITDEFPYYLRPKKAVFSAIICVALFLLGLILATDGG 446

  Fly   477 VVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLL 541
            :..:..|:.|..|..:|.:|......|...||:..|..|::.|||.||||:::.||.::|||.|:
 Frog   447 MYWLVLLDDYSAGFGLLVIVITFCLSVSRVYGIKNFCRDIQMMLGFKPGLYFKACWIFLSPVTLM 511

  Fly   542 TIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGCRQRLQESFQP 606
            .:..:||:.|:......|.:|.||..:|..:...|.:.||:.::.. ....:|...:|::::.:|
 Frog   512 CLLAYSILKYQPSQYGSYKFPLWSEALGILMGLLSCMMIPIGMLVA-ILKEEGSLWERIRQASRP 575

  Fly   607 EDNCGSVVPGQQGTSVXHDHAQVHVNIRTSCTSIK 641
            ..:        .|.|:..:...::||......|.|
 Frog   576 AMD--------WGPSMEENRTGMYVNTLAGSQSPK 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	234/540 (43%)
slc6a7	XP_002940131.3	SLC5-6-like_sbd	37..581	CDD:382020	235/553 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010