Protein Alignment SerT and slc6a2

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_017948962.2
• Gene: slc6a2 / 100486589
• XenbaseID: XB-GENE-486549
• Length: 624
• Species: Xenopus tropicalis
• Alignment Length: 609
• Identity: 306/609 - (50%)
• Similarity: 430/609 - (70%)
• Gaps: 26/609 - (4%)

  Fly    25 SDDKES---PNNEDDS----NEDDG-DHTTPAKVTDPLAPKLANNERILVVSVTERTRETWGQKA 81
            ||.|.|   |..:|..    .|.:| .:|:...:...|:|:..      |....::.||.||:|.
 Frog    12 SDHKLSAVAPEKKDVELILVKEQNGVQYTSSTVIVPDLSPQYE------VPGEGQQEREQWGKKI 70

  Fly    82 EFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIW 146
            :|||:|:||:|||.||||||::||:|||||||:||.||||..|:|||||||||||::|.|..::|
 Frog    71 DFLLSVVGFSVDLANVWRFPFLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVW 135

  Fly   147 KRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTENC------- 204
            | |||..|||||.:.||.:|:|.|||.||.|::|||.:||||:|||..|.|.||:.||
 Frog   136 K-ICPLFKGVGYTVILIALYVGFYYNVIIAWSLYYLVSSFTSELPWIKCGNEWNSLNCTDPMLLN 199

  Fly   205 MQVTSEN--FTELATSPAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVR 267
            |.:.|.|  :::..|:||.||:||.||..::.||:..:|..:..|.:|:..|.::::|||||||:
 Frog   200 MSMISYNTKYSKFKTTPAAEFYERGVLHLHESNGIHDLGQPRWQLTICLIVVLIVLFFSLWKGVK 264

  Fly   268 SAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPG 332
            ::|||||:||..|||||.:||:||::|||:.:||..||..:..:|.::.||||||:|||:|||.|
 Frog   265 TSGKVVWITATLPYVVLFVLLIRGITLPGSSKGISAYLHIDIKRLTDASVWIDAATQIFYSLGAG 329

  Fly   333 FGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLV 397
            ||.|:|.:|||||:||||||||:||:|||:|||::||.|||:|||||:....:|:.|..||.|||
 Frog   330 FGVLIAFASYNKFDNNCYRDALMTSTINCVTSFISGFAIFSILGYMAHKHNVNIEDVATEGAGLV 394

  Fly   398 FIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLA 462
            ||:|||||:|::||.||:::||:||:|||:||..||:||:||.|.|:. .::.|.|:||.||:..
 Frog   395 FIIYPEAISTLAGSTFWAVVFFIMLLTLGIDSAMGGMEAVITGLADDI-SILKRHRKLFTLLVAF 458

  Fly   463 FIFLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLF 527
            ..|:.||..:|.||:.::..|:.:..|.:|||.|.:||.||.|||||||||.|:.:|||.:|||:
 Frog   459 ITFIFALLCITNGGIYVLTLLDTFAAGTSILFAVLIEAIGVSWFYGVDRFSEDIHRMLGFRPGLY 523

  Fly   528 WRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFAS 592
            ||:||.::||.|||.:.|.||:.||.::.:||.:|.|:.:.|||:..||:..:|:||||| |...
 Frog   524 WRLCWKFVSPAFLLFVVIVSIVTYKPLMYDEYKFPPWANRTGWAIALSSMTLVPIYIIYK-FLTM 587

  Fly   593 KGGCRQRLQESFQPEDNCGSVVPG 616
            :|..|:||.....||:....|..|
 Frog   588 RGSLRERLAYCITPENEHHLVAQG 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	290/541 (54%)
slc6a2	XP_017948962.2	SLC5-6-like_sbd	63..622	CDD:382020	294/552 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	1	1.000	-	-		FOG0000975
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X639
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010