Protein Alignment SerT and slc6a15

DIOPT Version :9

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_002931668.1
• Gene: slc6a15 / 100380162
• XenbaseID: XB-GENE-975885
• Length: 730
• Species: Xenopus tropicalis
• Alignment Length: 729
• Identity: 234/729 - (32%)
• Similarity: 358/729 - (49%)
• Gaps: 141/729 - (19%)

  Fly    37 SNEDDGDHTTPAKVTDPLAPKLANNER-ILVVSVTERTRETWGQKAEFLLAVIGFAVDLGNVWRF 100
            ||||.||.:  .|.::.:.....:.:| |...|..:..|..|..|.:::||.:||:|.|||||||
 Frog    25 SNEDSGDES--FKKSELVVSDDVDKDRDIEEGSDIDDERPAWNSKLQYILAQVGFSVGLGNVWRF 87

  Fly   101 PYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDI 165
            ||:|.:|||||:||||.:.|:..|:|:|::||::||..|.|.:.:|..|.|.:.|:|:|.|::.:
 Frog    88 PYLCQKNGGGAYLVPYLILLLLIGIPVFFLELSVGQRIRRGSIGVWNYISPKMGGIGFASCIVCL 152

  Fly   166 YMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTENCMQVTSENFTE---LATSPAKEFFERK 227
            ::.:|||.||||:::|...||...|||..|....|..|       .|.|   ..:|....::.|:
 Frog   153 FVALYYNVIIGWSLFYFSQSFQHPLPWDQCPLVKNASN-------TFVEPECEKSSATTYYWYRE 210

  Fly   228 VL----ESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILL 288
            .|    ...:|.||::      .:.||:...::||..::.||::|:|||::.::|.|||||...|
 Frog   211 ALNISNSITEGGGLNW------KMTLCLLAAWILVCLAMIKGIQSSGKVMYFSSLFPYVVLTCFL 269

  Fly   289 VRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDA 353
            ||.:.|.|:.:||::..||:...:...|||.:||:|:||:||.|||.::|.|||||.:|||:.||
 Frog   270 VRALLLNGSVDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDA 334

  Fly   354 LITSSINCLTSFLAGFVIFSVLGYMA--------------------------------------- 379
            ::.|.||..||.||..|:|:|||:.|
 Frog   335 VLVSFINFFTSVLATLVVFAVLGFKANIMNENCISKNTVKIVKYLEAGNLSWSNVPHHVNFSSMS 399

  Fly   380 ------------YVQKTSIDKVGL-------------EGPGLVFIVYPEAIATMSGSVFWSIIFF 419
                        .:::...|.:||             :|.||.||.:.||:.....|.|||::||
 Frog   400 AQDYNLVYYIFQKIKEEEFDSLGLDSCQIEDELNKSVQGTGLAFIAFTEAMTHFPASPFWSVMFF 464

  Fly   420 LMLITLGLDSTFGGLEAMITALCDEY-----PRVIGRRRELFVLLLLAFIFLCALPTMTYGGVVL 479
            |||:.|||.|.||.:|.:||.:.|.:     |..:|       ..||||..  .|..:...|...
 Frog   465 LMLVNLGLGSMFGTIEGIITPIVDTFKVRKEPLTVG-------CCLLAFCI--GLLFVQRSGNYF 520

  Fly   480 VNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLLTIF 544
            |...:.|...|.:|.||.:|...:.|.||:|:|..|::.|||..|..::...|.||||| ||||.
 Frog   521 VTMFDDYSATLPLLIVVILENVAIAWVYGIDKFMDDLKDMLGFTPYKYYYYMWKYISPV-LLTIL 584

  Fly   545 I--------FSIMGYKEMLGEE-----YYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGC 596
            :        ||..||...:.|:     ..||.|...|..::...::|.:|:..|.:       .|
 Frog   585 LMASIVQMGFSPPGYYAWIAEKASEERISYPPWGLAVCISLIVFALLPVPVVFIVR-------TC 642

  Fly   597 RQRLQESFQPEDNCGSV--VPGQQG-----TSVXHDHAQ-VHVNIRTSCTS----IKIYNLNCSS 649
            .       ..:|:.||:  |..::|     ||. .|.|. :|..|::...|    ..||.....|
 Frog   643 N-------LIDDSTGSLASVSYKRGKMIKETSNLEDDASLIHEKIQSEMPSPNIGSSIYRKQSGS 700

  Fly   650 NSNSLSPTTSGAEG 663
            .:..:....:|..|
 Frog   701 PTLKVDTAPNGRYG 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	207/621 (33%)
slc6a15	XP_002931668.1	SLC5-6-like_sbd	61..640	CDD:382020	206/601 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920