Protein Alignment SerT and slc6a11b

DIOPT Version :10

• Sequence 1: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_073772263.1
• Gene: slc6a11b / 100150472
• ZFINID: ZDB-GENE-121116-2
• Length: 617
• Species: Danio rerio
• Alignment Length: 572
• Identity: 253/572 - (44%)
• Similarity: 371/572 - (64%)
• Gaps: 22/572 - (3%)

  Fly    49 KVTDPLAPKLAN------NERILVVSVTERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQN 107
            |..:.:.|:.||      |::.:|     ..|..|..|.||:|:|.|..:.|||||||||:||:|
Zfish    13 KAEESMDPESANPSVVRSNDKKVV-----NERGQWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKN 72

  Fly   108 GGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYN 172
            |||||.|||.:|.:..|:|:|::|.|||||...|.::.|:::||..:|:|||..:|:.::.:||.
Zfish    73 GGGAFFVPYVIFFVCCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYV 137

  Fly   173 TIIGWAVYYLFASFTSKLPWTSCDNPWNTENCMQVTSE---NFTE-LATSPAKEFFERKVLESYK 233
            .|:.||::|||..||::|||.||.:.||||||:...:|   |||. .:|||..||:||:||:.
Zfish   138 VILAWAIFYLFNCFTTELPWASCGHYWNTENCVDFNNESIANFTNPYSTSPVMEFWERRVLKI-- 200

  Fly   234 GNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGAD 298
            .:|::.:|.::..||||:...:|:.||.:|||.:|.||||:|||..||.:|:|||:||::||||.
Zfish   201 SSGIEEVGGLRWELALCLAIAWVICYFCIWKGPKSTGKVVYVTATFPYFMLLILLLRGITLPGAA 265

  Fly   299 EGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLT 363
            .|||:||.|:..:|.:.:||:||.:|||||.....|.|.||.|||.:|||||||.|:...:|..|
Zfish   266 NGIKFYLYPDISRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNSYNNNCYRDCLMLCCLNSGT 330

  Fly   364 SFLAGFVIFSVLGYMAYVQKTSIDKVGLEGPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLD 428
            ||:|||.||||||:|||.|...|:.|...||||.||.||:|:..|..:..|:.:||:|||.||||
Zfish   331 SFVAGFAIFSVLGFMAYEQNVPIEAVAESGPGLAFIAYPKAVTMMPWAPLWAALFFMMLIFLGLD 395

  Fly   429 STFGGLEAMITALCDEYPRV--IGRRRELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVY-GPGL 490
            |.|..:|:::||:.|.||:.  :|.||||.:|.:....|...|..:|.||:.:....:.| ..|:
Zfish   396 SQFVCVESLVTAIVDMYPKTFRVGYRRELLILGMSIASFFLGLIMLTEGGMYVFQLFDSYAASGM 460

  Fly   491 AILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEM- 554
            .:|||...|:..:.|.||.|||..::|.|:|.||..|.:.||.:.:|.....||:|.::.||.:
Zfish   461 CLLFVAIFESICIGWVYGSDRFYMNIEDMIGYKPIFFIKWCWKFFTPGICTGIFLFFLIKYKPLK 525

  Fly   555 LGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGCRQRLQESFQP 606
            ....|.||||.|.:||.:..||::|||:.|::: .:.:||..|:|:::...|
Zfish   526 YNNVYTYPDWGYGIGWMMAMSSMVCIPLGILFQ-IWKTKGTFRERIKKLTTP 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	247/541 (46%)
slc6a11b	XP_073772263.1	None