DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn8 and MEE34

DIOPT Version :9

Sequence 1:	NP_001261167.1	Gene:	Rpn8 / 37894	FlyBaseID:	FBgn0002787	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_187736.1	Gene:	MEE34 / 820298	AraportID:	AT3G11270	Length:	310	Species:	Arabidopsis thaliana

Alignment Length:	311	Identity:	172/311 - (55%)
Similarity:	237/311 - (76%)	Gaps:	17/311 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SQEVS---VNKVIVHPLVLLSVVDHFNRMGKIGNQKRVVGVLLGCWRSKGVLDVSNSFAVPFDED 64
            :|::|   :.|||||||||||:|||:||:.| ...|||||||||. .|:|.:||:||:||||:||
plant     6 TQQISARTIEKVIVHPLVLLSIVDHYNRVAK-DTSKRVVGVLLGS-SSRGTVDVTNSYAVPFEED 68

  Fly    65 DKDKSVWFLDHDYLENMYGMFKKVNARERVVGWYHTGPKLHQNDIAINELVRRYCPNSVLVIIDA 129
            |||.|:|||||:|.|:|:.|||::||:|.:||||.|||||.:||:.::.|...|.||.||||||.
plant    69 DKDTSIWFLDHNYHESMFHMFKRINAKEHIVGWYSTGPKLRENDLDVHALFNGYVPNPVLVIIDV 133

  Fly   130 KPKDLGLPTEAYISVEEVHDDGSPTS-KTFEHVPSEIGAEEAEEVGVEHLLRDIKDTTVGSLSQK 193
            :||:||:||:||.:||||.::.:..| :.|.|||:||.|.|.||:||||||||:||||:.:|:.:
plant   134 QPKELGIPTKAYYAVEEVKENATQKSQQVFVHVPTEIAAHEVEEIGVEHLLRDVKDTTISTLATE 198

  Fly   194 ITNQLMGLKGLNAQLRDIKQYLQRVGDSKMPINHQIVYQLQDIFNLLPDITNDQFTGTMYVKTND 258
            :|.:|..||||:|:||:|:.||..|.:.|:|:||:|:|.|||:|||||::..::......|||||
plant   199 VTAKLTALKGLDARLREIRTYLDLVIEGKLPLNHEILYHLQDVFNLLPNLNVNELVKAFAVKTND 263

  Fly   259 QMLVVYLASMVRSIIALHNLINNKLANRDAEEGKSDSKEAKEKNKDSKDKD 309
            .|||:||:|::||:||||:||||||.|::           .||.:|||..|
plant   264 MMLVIYLSSLIRSVIALHSLINNKLLNKE-----------HEKAEDSKPVD 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn8	NP_001261167.1	PLN03246	7..308	CDD:215645	170/304 (56%)
Rpn8	NP_001261167.1	MPN_RPN7_8	9..290	CDD:163693	164/281 (58%)
MEE34	NP_187736.1	PLN03246	10..310	CDD:215645	171/307 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	154	1.000	Domainoid score	I1354
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2104
Inparanoid	1	1.050	353	1.000	Inparanoid score	I607
OMA	1	1.010	-	-		QHG53821
OrthoDB	1	1.010	-	-		D1275837at2759
OrthoFinder	1	1.000	-	-		FOG0003980
OrthoInspector	1	1.000	-	-		otm3000
orthoMCL	1	0.900	-	-		OOG6_102054
Panther	1	1.100	-	-	O	PTHR10540
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2737
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.880