DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn8 and stambpa

DIOPT Version :9

Sequence 1:	NP_001261167.1	Gene:	Rpn8 / 37894	FlyBaseID:	FBgn0002787	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_956792.1	Gene:	stambpa / 797422	ZFINID:	ZDB-GENE-040426-1551	Length:	418	Species:	Danio rerio

Alignment Length:	187	Identity:	36/187 - (19%)
Similarity:	66/187 - (35%)	Gaps:	48/187 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PSQEVSV-NKVIVHPL----VLLSVVDHFNRMGKIGNQKRV--VGVLLGCWRSKGVLDVSNSFAV 59
            ||..||. :..:|:.|    |...:...|.::.:....:.|  .|:|.|..       :.|:|.|
Zfish   233 PSVPVSAGHSALVNGLRQLFVPAELCQRFLKLAETNTARAVETCGILCGKL-------MKNAFTV 290

  Fly    60 -----------PFDEDDKDKSVWFLDHDYLENMYGMFKKVNARERVVGWYHTGPK----LHQNDI 109
                       |...|.:::...||..|..:.:            .:||.||.|.    |...|:
Zfish   291 THVIVPKQCGGPDYCDTENEEELFLIQDQNDLI------------TLGWIHTHPTQTAFLSSVDL 343

  Fly   110 AINELVRRYCPNSVLVIIDAKPKDLGLPTEAYISVEE--VHDDGSPTSKTFEHVPSE 164
            ..:...:...|.|:.::...|..:.|     |..:.:  :.|.|:...:.|...|.:
Zfish   344 HTHCSYQMMLPESIAIVCSPKFNETG-----YFRLTDYGMDDVGTCKQRGFHPHPKD 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn8	NP_001261167.1	PLN03246	7..308	CDD:215645	33/182 (18%)
Rpn8	NP_001261167.1	MPN_RPN7_8	9..290	CDD:163693	32/179 (18%)
stambpa	NP_956792.1	USP8_dimer	13..114	CDD:286108
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	199..218
		MPN_AMSH_like	248..418	CDD:163697	31/172 (18%)
		JAMM motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01182	329..342		4/12 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900