DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn8 and stambpb

DIOPT Version :9

Sequence 1:	NP_001261167.1	Gene:	Rpn8 / 37894	FlyBaseID:	FBgn0002787	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_001032659.1	Gene:	stambpb / 641572	ZFINID:	ZDB-GENE-051127-31	Length:	418	Species:	Danio rerio

Alignment Length:	206	Identity:	41/206 - (19%)
Similarity:	69/206 - (33%)	Gaps:	58/206 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PLVLLSVVDHFNRM-------GKI-----GNQKRVV---GVLLGCWRSKGVLDVSNSFAV----- 59
            |..|.:::|...::       ||.     .|..|.|   |:|.|...       .|:|.|
Zfish   238 PSHLTTLIDGLRQIAVPAELCGKFLRLANNNTIRAVETCGILCGTLN-------RNAFTVTHVVV 295

  Fly    60 ------PFDEDDKDKSVWFLDHDYLENMYGMFKKVNARERVVGWYHTGPK----LHQNDIAINEL 114
                  |...|.:::...||    :::.|.:.        .:||.||.|.    |...|:..:..
Zfish   296 PKQCGGPDYCDTENEEELFL----VQDQYNLI--------TLGWIHTHPTQTAFLSSVDLHTHCS 348

  Fly   115 VRRYCPNSVLVIIDAKPKDLGLPTEAYISVEEVHDDGSPTSKTFEHVPSEIGAEEAEEVGVEHLL 179
            .:...|.|:.::...|....|........:||:   .:...|.|...|.    :.....|..|::
Zfish   349 YQMMLPESIAIVCSPKFNQTGYFRLTDYGMEEI---STCAQKGFHPHPK----DPPLFTGGSHII 406

  Fly   180 RDIKDTTVGSL 190
              |.:.||..|
Zfish   407 --ITEDTVSML 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn8	NP_001261167.1	PLN03246	7..308	CDD:215645	41/206 (20%)
Rpn8	NP_001261167.1	MPN_RPN7_8	9..290	CDD:163693	41/206 (20%)
stambpb	NP_001032659.1	USP8_dimer	13..116	CDD:286108
stambpb	NP_001032659.1	MPN_AMSH_like	248..418	CDD:163697	38/196 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900