Protein Alignment Rpn8 and PSMD7

DIOPT Version :9

• Sequence 1: NP_001261167.1
• Gene: Rpn8 / 37894
• FlyBaseID: FBgn0002787
• Length: 358
• Species: Drosophila melanogaster
• Sequence 2: NP_002802.2
• Gene: PSMD7 / 5713
• HGNCID: 9565
• Length: 324
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 256/342 - (74%)
• Similarity: 297/342 - (86%)
• Gaps: 18/342 - (5%)

  Fly     1 MPSQEVSVNKVIVHPLVLLSVVDHFNRMGKIGNQKRVVGVLLGCWRSKGVLDVSNSFAVPFDEDD 65
            ||  |::|.||:|||||||||||||||:||:||||||||||||.|:.| ||||||||||||||||
Human     1 MP--ELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKK-VLDVSNSFAVPFDEDD 62

  Fly    66 KDKSVWFLDHDYLENMYGMFKKVNARERVVGWYHTGPKLHQNDIAINELVRRYCPNSVLVIIDAK 130
            ||.|||||||||||||||||||||||||:|||||||||||:||||||||::||||||||||||.|
Human    63 KDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVK 127

  Fly   131 PKDLGLPTEAYISVEEVHDDGSPTSKTFEHVPSEIGAEEAEEVGVEHLLRDIKDTTVGSLSQKIT 195
            |||||||||||||||||||||:|||||||||.||||||||||||||||||||||||||:|||:||
Human   128 PKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRIT 192

  Fly   196 NQLMGLKGLNAQLRDIKQYLQRVGDSKMPINHQIVYQLQDIFNLLPDITNDQFTGTMYVKTNDQM 260
            ||:.||||||::|.||:.||::|...|:||||||:|||||:||||||::..:|....|:||||||
Human   193 NQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDVSLQEFVKAFYLKTNDQM 257

  Fly   261 LVVYLASMVRSIIALHNLINNKLANRDAEEGKSDSKEAKEKNKDSKDKDNKETKDKDGKKAEEKA 325
            :||||||::||::|||||||||:||||||:     ||.:||.:..||:  ||.|:||  |.:||:
Human   258 VVVYLASLIRSVVALHNLINNKIANRDAEK-----KEGQEKEESKKDR--KEDKEKD--KDKEKS 313

  Fly   326 DKGKDEGGKGSRKXERK 342
            |..|:|      |.|:|
Human   314 DVKKEE------KKEKK 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpn8	NP_001261167.1	PLN03246	7..308	CDD:215645	238/300 (79%)
		MPN_RPN7_8	9..290	CDD:163693	231/280 (83%)
PSMD7	NP_002802.2	MPN_RPN7_8	7..285	CDD:163693	229/278 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..324		25/57 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147334
Domainoid	1	1.000	218	1.000	Domainoid score	I2668
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2104
Inparanoid	1	1.050	515	1.000	Inparanoid score	I1309
Isobase	1	0.950	-	0	Normalized mean entropy	S277
OMA	1	1.010	-	-		QHG53821
OrthoDB	1	1.010	-	-		D1275837at2759
OrthoFinder	1	1.000	-	-		FOG0003980
OrthoInspector	1	1.000	-	-		oto89120
orthoMCL	1	0.900	-	-		OOG6_102054
Panther	1	1.100	-	-	LDO	PTHR10540
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1207
SonicParanoid	1	1.000	-	-		X2737
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	16	15.790