DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn8 and psmd7

DIOPT Version :9

Sequence 1:	NP_001261167.1	Gene:	Rpn8 / 37894	FlyBaseID:	FBgn0002787	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_956083.1	Gene:	psmd7 / 327330	ZFINID:	ZDB-GENE-030131-5541	Length:	327	Species:	Danio rerio

Alignment Length:	329	Identity:	249/329 - (75%)
Similarity:	291/329 - (88%)	Gaps:	5/329 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPSQEVSVNKVIVHPLVLLSVVDHFNRMGKIGNQKRVVGVLLGCWRSKGVLDVSNSFAVPFDEDD 65
            ||  :::|.:|:|||||||||||||||:||:|:||||||||||.|:.| ||||||||||||||||
Zfish     1 MP--DLAVERVVVHPLVLLSVVDHFNRIGKVGSQKRVVGVLLGSWQKK-VLDVSNSFAVPFDEDD 62

  Fly    66 KDKSVWFLDHDYLENMYGMFKKVNARERVVGWYHTGPKLHQNDIAINELVRRYCPNSVLVIIDAK 130
            ||.|||||||||||||||||||||||||:|||||||||||:||||||||:::||.||||||||.|
Zfish    63 KDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKQYCSNSVLVIIDVK 127

  Fly   131 PKDLGLPTEAYISVEEVHDDGSPTSKTFEHVPSEIGAEEAEEVGVEHLLRDIKDTTVGSLSQKIT 195
            |||||||||||||||||||||:|||||||||.||||||||||||||||||||||||||:|||:||
Zfish   128 PKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRIT 192

  Fly   196 NQLMGLKGLNAQLRDIKQYLQRVGDSKMPINHQIVYQLQDIFNLLPDITNDQFTGTMYVKTNDQM 260
            ||:.||||||::|.|||.||::|...|:||||||:|||||:||||||:...:|....|:||||||
Zfish   193 NQVHGLKGLNSKLLDIKSYLEKVATGKLPINHQIIYQLQDVFNLLPDVNLQEFVKAFYLKTNDQM 257

  Fly   261 LVVYLASMVRSIIALHNLINNKLANRDAEEGKSDSK-EAKEKNKDSKDKDNKETKDKDGK-KAEE 323
            |||||||::||::|||||||||:||||||:.:...| ::|::.||.||||..:.|:||.. |.|:
Zfish   258 LVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKDDSKKEKKDEKDKDKDKDKEKDASAKKED 322

  Fly   324 KADK 327
            |.||
Zfish   323 KKDK 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn8	NP_001261167.1	PLN03246	7..308	CDD:215645	236/301 (78%)
Rpn8	NP_001261167.1	MPN_RPN7_8	9..290	CDD:163693	229/280 (82%)
psmd7	NP_956083.1	PLN03246	6..290	CDD:215645	231/284 (81%)
psmd7	NP_956083.1	MPN_RPN7_8	7..287	CDD:163693	229/280 (82%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580869
Domainoid	1	1.000	209	1.000	Domainoid score	I2795
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2104
Inparanoid	1	1.050	495	1.000	Inparanoid score	I1352
OMA	1	1.010	-	-		QHG53821
OrthoDB	1	1.010	-	-		D1275837at2759
OrthoFinder	1	1.000	-	-		FOG0003980
OrthoInspector	1	1.000	-	-		oto39219
orthoMCL	1	0.900	-	-		OOG6_102054
Panther	1	1.100	-	-	LDO	PTHR10540
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1207
SonicParanoid	1	1.000	-	-		X2737
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.940