DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn8 and Mysm1

DIOPT Version :9

Sequence 1:	NP_001261167.1	Gene:	Rpn8 / 37894	FlyBaseID:	FBgn0002787	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	XP_008762133.1	Gene:	Mysm1 / 298247	RGDID:	1311787	Length:	811	Species:	Rattus norvegicus

Alignment Length:	223	Identity:	44/223 - (19%)
Similarity:	82/223 - (36%)	Gaps:	64/223 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 VVGWYHTGPKLHQNDIAINELVRRYCPNSVLVIIDAKPKDLGLPTEAYISVEEVHDDG---SPTS 155
            |:||||:.|              .:.||..|..||.:.|     .::|.|.......|   ||.:
  Rat   634 VIGWYHSHP--------------AFDPNPSLRDIDTQAK-----YQSYFSRGGAKFIGMIVSPYN 679

  Fly   156 KT----FEHVPSEIGAEEAEEVG---------VEHLLRDIKDTTVGSLSQKITNQLMGLKGLNAQ 207
            ::    :..:...:.:||....|         |:.:|.:.:...|...::.|
  Rat   680 RSNPLPYSQITCLVISEELSPDGTYRLPYKFEVQQMLEEPQWELVFEKTRWI------------- 731

  Fly   208 LRDIKQYLQRVGDSKMPINHQIVYQLQDIFNLLPDITNDQFTGTMYVKTNDQMLVVYLASMVRSI 272
               |::|  |:..|.:|::.        ||....|:|..|.......||..::...::|.  ..:
  Rat   732 ---IEKY--RLSHSSVPMDR--------IFRRDSDLTCLQKLLECLRKTLSKVANCFIAE--EFL 781

  Fly   273 IALHNLINNKLANRDAEEGKSDSKEAKE 300
            ..:.||..:...::: |.|.::...|||
  Rat   782 TQVENLFLSNYKSKE-ENGLAEENSAKE 808

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn8	NP_001261167.1	PLN03246	7..308	CDD:215645	44/223 (20%)
Rpn8	NP_001261167.1	MPN_RPN7_8	9..290	CDD:163693	39/211 (18%)
Mysm1	XP_008762133.1	Myb_DNA-binding	116..160	CDD:395191
		SWIRM	365..444	CDD:398234
		MPN_2A_DUB	554..736	CDD:163698	26/138 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900