Protein Alignment Rpn8 and Cops5

DIOPT Version :10

• Sequence 1: NP_001261167.1
• Gene: Rpn8 / 37894
• FlyBaseID: FBgn0002787
• Length: 358
• Species: Drosophila melanogaster
• Sequence 2: NP_038743.1
• Gene: Cops5 / 26754
• MGIID: 1349415
• Length: 334
• Species: Mus musculus
• Alignment Length: 319
• Identity: 67/319 - (21%)
• Similarity: 121/319 - (37%)
• Gaps: 90/319 - (28%)

  Fly    13 VHPLVLLSVVDHFNRMGKIGNQKRVVGVLLGCWRSKGVLDVSNSFAVPFDEDDKDKSVWFLDHDY 77
            :..|.||.:|.|    .:.|....|:|::||....:.:: :.:|||:|.:..:...:.....::|
Mouse    57 ISALALLKMVMH----ARSGGNLEVMGLMLGKVDGETMI-IMDSFALPVEGTETRVNAQAAAYEY 116

  Fly    78 LENMYGMFKKVNARERVVGWYHTGPK----LHQNDIAINELVRRYCPNSVLVIIDAKPKDLGLPT 138
            :.......|:|...|..:||||:.|.    |...|::...|.:::....|.|:||        ||
Mouse   117 MAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVID--------PT 173

  Fly   139 EAYISVEEVH--------------DDGSPTSKTFEHVPSE---IGAEEAEEVGV---EHLLRDIK 183
            .. ||..:|:              |:|          |||   |...:.|:.||   ::...::
Mouse   174 RT-ISAGKVNLGAFRTYPKGYKPPDEG----------PSEYQTIPLNKIEDFGVHCKQYYALEV- 226

  Fly   184 DTTVGSLSQKITNQLMGLKGLNAQLRDIKQYLQRVGDSKMPINHQIVYQLQDIFNLLPDI----- 243
            .....||.:|:...|..           |.::..:..|.:..|..  |....:|:|...:
Mouse   227 SYFKSSLDRKLLELLWN-----------KYWVNTLSSSSLLTNAD--YTTGQVFDLSEKLEQSEA 278

  Fly   244 ------------TNDQFTGTMYVKTNDQMLVVYLASMVRSIIALHNL----INNKLANR 286
                        |:|:       |:.|::......|...:|.|:|.|    |.:||.|:
Mouse   279 QLGRGSFMLGLETHDR-------KSEDKLAKATRDSCKTTIEAIHGLMSQVIKDKLFNQ 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpn8	NP_001261167.1	MPN_RPN7_8	9..290	CDD:163693	67/319 (21%)
Cops5	NP_038743.1	MPN_RPN11_CSN5	44..314	CDD:163700	60/301 (20%)
		JAMM motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01182	138..151		3/12 (25%)