Protein Alignment Slik and STE7

DIOPT Version :10

• Sequence 1: NP_726441.1
• Gene: Slik / 37893
• FlyBaseID: FBgn0035001
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: NP_010122.1
• Gene: STE7 / 851396
• SGDID: S000002318
• Length: 515
• Species: Saccharomyces cerevisiae
• Alignment Length: 338
• Identity: 102/338 - (30%)
• Similarity: 172/338 - (50%)
• Gaps: 46/338 - (13%)

  Fly    40 VGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEEN--LSDHMVEIDILSEIK-HPNIVELYEAF 101
            :|::|.|..|.|.||.|....:..|.|...:|...:  ::..:.|:.|:..:| |.||:..|.|:
Yeast   194 LGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAY 258

  Fly   102 ---SIDDKLWMLIEYCDGGALDSIM-----------VELEK----PLTEPQIAYVCKHMTEGLTF 148
               .|::::.:|:||.|.|:||.|:           |..:|    .||..:|||   .:..||..
Yeast   259 YNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAY---GVLNGLDH 320

  Fly   149 LHRN-KVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRD 212
            |:|. |:||||:|..|||:..:|.:||.|||||.|..:::.  |||:||..:|:||.:     :.
Yeast   321 LYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIA--DTFVGTSTYMSPERI-----QG 378

  Fly   213 NPYDHKVDIWSLGITLIELAQMEPP--NSEMSPMRVLLKIQK--SEP-PKLEQPSRWSKEFNDFL 272
            |.|..|.|:||||:.:|||...|.|  ....:|..:|..:|:  :|| |:|.:...:|||..||:
Yeast   379 NVYSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFV 443

  Fly   273 KKSLVKDPQVRPTTDVLMQHAFINRNLDAKPIKDLLLEYKAEVVEEVVDDETEEPRNSALQLDLD 337
            .:..:|:.:.|.:...|:.|..|.:.:  .|.||....:....::..:.::....|.:.
Yeast   444 NRCCIKNERERSSIHELLHHDLIMKYV--SPSKDDKFRHWCRKIKSKIKEDKRIKREAL------ 500

  Fly   338 DDSASLQSQDIDK 350
             |.|.|:.:..::
Yeast   501 -DRAKLEKKQSER 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slik	NP_726441.1	STKc_SLK_like	31..310	CDD:132942	98/296 (33%)
		PKK	958..1095	CDD:463600
		PKK	1126..1266	CDD:463600
STE7	NP_010122.1	PKc_Byr1_like	185..482	CDD:270792	98/299 (33%)