Protein Alignment Slik and map2k1

DIOPT Version :10

• Sequence 1: NP_726441.1
• Gene: Slik / 37893
• FlyBaseID: FBgn0035001
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: NP_001008058.1
• Gene: map2k1 / 493420
• XenbaseID: XB-GENE-478822
• Length: 395
• Species: Xenopus tropicalis
• Alignment Length: 353
• Identity: 109/353 - (30%)
• Similarity: 170/353 - (48%)
• Gaps: 73/353 - (20%)

  Fly     5 TNL----KKVFHLGGGEAKKKRLYNNIKMDTDPAEF----WEMVGELGDGAFGKVYKAQHKEQKR 61
            |||    ||:..|...|.::|||...:.......|.    :|.|.|||.|..|.|:|..||....
 Frog    28 TNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKVSELGAGNGGVVFKVSHKPTSL 92

  Fly    62 FAAAKMCQLEDEENLSDHMV-EIDILSEIKHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVE 125
            ..|.|:..||.:..:.:.:: |:.:|.|...|.||..|.||..|.::.:.:|:.|||:||.::.:
 Frog    93 IMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKK 157

  Fly   126 L----EKPLTEPQIAYVCKHMTEGLTFL-HRNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKH 185
            .    ||.|.:..||.:     :|||:| .::|::|||:|..|:|:...|.:||.|||||.:...
 Frog   158 AGKIPEKILGKVSIAVI-----KGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLID 217

  Fly   186 TMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELA------------------ 232
            :|.  ::|:||..:|:|     |..:...|..:.||||:|::|:|:|
 Frog   218 SMA--NSFVGTRSYMSP-----ERLQGTHYSVQSDIWSMGLSLVEMAIGRYPIPPPDAKELELIF 275

  Fly   233 ----QMEPPNSEMSP----------------------MRVLLKIQKSEPPKLEQPSR-WSKEFND 270
                :.:|.:||::|                      ..:|..|....||||  ||. :..||.|
 Frog   276 GCSVEGDPASSELAPRPRPPGRPISSYGPDSRPPMAIFELLDYIVNEPPPKL--PSGVFGAEFQD 338

  Fly   271 FLKKSLVKDPQVRPTTDVLMQHAFINRN 298
            |:.|.|||:|..|.....||.|:||.::
 Frog   339 FVNKCLVKNPAERADLKQLMVHSFIKQS 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slik	NP_726441.1	STKc_SLK_like	31..310	CDD:132942	99/323 (31%)
		PKK	958..1095	CDD:463600
		PKK	1126..1266	CDD:463600
map2k1	NP_001008058.1	PKc_MEK1	62..382	CDD:270816	99/319 (31%)