Protein Alignment Slik and pak1

DIOPT Version :10

• Sequence 1: NP_726441.1
• Gene: Slik / 37893
• FlyBaseID: FBgn0035001
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: XP_021323273.1
• Gene: pak1 / 373103
• ZFINID: ZDB-GENE-030826-29
• Length: 587
• Species: Danio rerio
• Alignment Length: 276
• Identity: 108/276 - (39%)
• Similarity: 156/276 - (56%)
• Gaps: 10/276 - (3%)

  Fly    32 DPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKHPNIVE 96
            ||.:.:....::|.||.|.||.|......:..|.|...|:.:......:.||.::.|.|:||||.
Zfish   307 DPKKKYTRFEKIGQGASGTVYTAIDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVN 371

  Fly    97 LYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKA 161
            ..:::.:.|:||:::||..||:|..::.  |..:.|.|||.||:...:.|.|||.|:|||||:|:
Zfish   372 YLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEAQIAAVCRECLQALEFLHCNQVIHRDIKS 434

  Fly   162 GNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGI 226
            .|:||.|:|.|||.|||..|:......|..|.:|||||||||:|..:.     |..|||||||||
Zfish   435 DNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-----YGPKVDIWSLGI 494

  Fly   227 TLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQ 291
            ..||:.:.|||....:|:|.|..|..:..|:|:.|.:.|..|.|||.:.|..|.:.|.:...|:|
Zfish   495 MAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAVFRDFLNRCLEMDVEKRGSAKELLQ 559

  Fly   292 HAFINRNLDAKPIKDL 307
            |.|:.   .|||:..|
Zfish   560 HQFLK---VAKPLSSL 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slik	NP_726441.1	STKc_SLK_like	31..310	CDD:132942	108/276 (39%)
		PKK	958..1095	CDD:463600
		PKK	1126..1266	CDD:463600
pak1	XP_021323273.1	PBD	73..130	CDD:395634
		Protein Kinases, catalytic domain	283..586	CDD:473864	108/276 (39%)