Protein Alignment Slik and pak2a

DIOPT Version :10

• Sequence 1: NP_726441.1
• Gene: Slik / 37893
• FlyBaseID: FBgn0035001
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: NP_001002717.1
• Gene: pak2a / 266749
• ZFINID: ZDB-GENE-021011-2
• Length: 517
• Species: Danio rerio
• Alignment Length: 276
• Identity: 109/276 - (39%)
• Similarity: 156/276 - (56%)
• Gaps: 10/276 - (3%)

  Fly    32 DPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKHPNIVE 96
            ||.:.:....::|.||.|.||.|......:..|.|...|:.:......:.||.::.|:|:||||.
Zfish   237 DPKKKYTRYEKIGQGASGTVYTAIDVATGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVN 301

  Fly    97 LYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKA 161
            ..::|.:.|:|::::||..||:|..::.  |..:.|.|||.||:...:.|.|||.|:|||||:|:
Zfish   302 FLDSFLVGDELFVVMEYLAGGSLTDVVT--ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKS 364

  Fly   162 GNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGI 226
            .||||.|:|.|||.|||..|:......|..|.:|||||||||:|..:.     |..|||||||||
Zfish   365 DNVLLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-----YGPKVDIWSLGI 424

  Fly   227 TLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQ 291
            ..||:.:.|||....:|:|.|..|..:..|:|:.|.:.|..|.|||.:.|..|.:.|.....|:|
Zfish   425 MAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGGGKELLQ 489

  Fly   292 HAFINRNLDAKPIKDL 307
            |.|:..   |||:..|
Zfish   490 HPFLKL---AKPLSSL 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slik	NP_726441.1	STKc_SLK_like	31..310	CDD:132942	109/276 (39%)
		PKK	958..1095	CDD:463600
		PKK	1126..1266	CDD:463600
pak2a	NP_001002717.1	PBD	74..131	CDD:395634
		STKc_PAK2	222..517	CDD:132986	109/276 (39%)