Protein Alignment Slik and si:dkey-81j8.6

DIOPT Version :9

• Sequence 1: NP_726441.1
• Gene: Slik / 37893
• FlyBaseID: FBgn0035001
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: XP_005155384.1
• Gene: si:dkey-81j8.6 / 101885880
• ZFINID: ZDB-GENE-091116-12
• Length: 1293
• Species: Danio rerio
• Alignment Length: 1406
• Identity: 427/1406 - (30%)
• Similarity: 668/1406 - (47%)
• Gaps: 249/1406 - (17%)

  Fly     7 LKKVFHLGGGEAKKKRLYNNIKMDTDPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLE 71
            |.:.|.| |.|.|:.|.|.|:|.|.||.:.||.:|||||||||||||||::......|.|:.::.
Zfish     5 LMRFFRL-GVEKKRVRHYENLKRDVDPHQSWETLGELGDGAFGKVYKAQNQTTGVLGAVKVIEVR 68

  Fly    72 DEENLSDHMVEIDILSEIKHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIA 136
            .||.|.|::.|||||:..:||||:.|.:|...:..||:|:|||.|||||.||:|||:.|||.||:
Zfish    69 SEEQLDDYITEIDILAACRHPNILSLLDAIFFEGWLWILLEYCPGGALDDIMLELERGLTEQQIS 133

  Fly   137 YVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMA 201
            .||....:.|.:||::.:|||||||||:||||:|.||||||||||||.:|:||..||||||||||
Zfish   134 EVCWQTLQALFYLHQHHIIHRDLKAGNILLTMDGQVKLADFGVSAKNDYTLQKRSTFIGTPYWMA 198

  Fly   202 PELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSK 266
            ||:::|||.:||||..|.||||:||||||.|:||||:..::||||||||.||.||.|..|.:||.
Zfish   199 PEVIMCETSKDNPYTSKADIWSMGITLIEAAEMEPPHHSLNPMRVLLKITKSPPPTLSNPRQWSS 263

  Fly   267 EFNDFLKKSLVKDPQVRPTTDVLMQHAFINRNLDAKPIKDLLLEYKAEVVEEVVDDET------- 324
            .|.|||::||.|:|:.|..|..||.|.|.....|.:.:|:|:.|.||||. |||::|:
Zfish   264 HFQDFLRRSLQKNPEARWGTQQLMAHPFSYAGRDGRALKELIAEAKAEVT-EVVENESLFNIQSS 327

  Fly   325 -EEPRNSALQLDLDDDSASLQSQDIDKLPGTP--TSILRDAKEQSQPSSSL-PIAAAATAAAAAT 385
             |:...:..:..|.....:::.|...: |.||  ||:| |...||..:|.| |.......|:.||
Zfish   328 VEDTITTESEKTLPRPEQAIEEQGPQE-PETPKKTSVL-DTVPQSPINSELNPEVKVTRRASQAT 390

  Fly   386 TTTKATTPDR----PNH-------------------------TKDDNAEAAAQQPPHTKVPAPAP 421
            ...|.....|    |.:                         ||:....:||:    |....|:.
Zfish   391 NQVKTQKRARRLSVPGNLLSFLSGGSRRCKSGFWGDNSPVQVTKNSEDSSAAE----TVGTCPSD 451

  Fly   422 -PSSQQTPPPQVQQPPTPPAQPTAAVLQKKPE-DV----------AAVAETSEKTESDKKHFVKK 474
             ..|:.|..|:.:.|....| |:..|...|.| |.          :|.|:|:..:|||
Zfish   452 GTESENTAKPKEETPDVVDA-PSNKVADIKDEVDTEETDKNLNLSSAPAQTTVSSESD------- 508

  Fly   475 GKAPPPPSPLGLANAKPAASD-----------SQTSPKKLATP----------EPTSPVTTAIEV 518
                    .|||......|::           .||..|.|..|          ..|..|...:|.
Zfish   509 --------TLGLTKEDTEAAEKRNGTVTNSDNDQTFWKSLQIPAVLDKDATHQHSTQVVALCLET 565

  Fly   519 AIGQEAMEPKPQP------PSPTASSIVSVQSVASSSSSGSV-------------SNAVLSSSTS 564
            .:..:....:..|      ..|..:|..::.:..:.....|:             |...|.:..:
Zfish   566 TLALKTNRNEENPNDYLNLACPLKTSTFTLDNTKTPKVPSSIFPERAPDFKNEQPSTEPLETEET 630

  Fly   565 LITINSDPPTPHHHQPLPPQPQ------HLILPNSLESVSQITVVTSTHPPVIIDNSVMPPQNEV 623
            :..:.:|..|....:.|..:.|      |:.:....|..:::......|..|..:|.....:.
Zfish   631 VEELETDGGTEEESRLLETEDQTITKEDHIAMKVESEDFTEVISEGVRHEDVNSNNEKSEEEE-- 693

  Fly   624 IIVSNDMNKSTHLHESSTDDDFPSLDDSLGDATTPPHKQSSMILAVNEPAGVVPAPPSQPQTSST 688
               |::.:|.|...|.||..:..::.|...|           :.::||.:.:
Zfish   694 ---SSEKDKETTEEECSTSKEEDTMKDDHED-----------VDSINENSEI------------- 731

  Fly   689 VHARKLDESEVLIVSPSYADDDSAYNTASGSHSHDHSDHL-MDTSHVSVVTVGDEGVKVKDSSNE 752
              :||.||.   :.:|...:..:..::.:...|:...|:| .:||:..|.....:..:.::...|
Zfish   732 --SRKSDEE---METPIQNETTNITDSQTPEMSNKEEDNLEKETSNEGVAQDATDSKEPEEEFPE 791

  Fly   753 LVKRQPNGVGIVPEDV---NIIVNRFKQEKRSPDSSLSENGSVRGRRGIEVLVGGSGGSDVDSIG 814
            :....|:......:|.   ..:|:..|.:|:       ....|:..:..|.|..|.  :|.||:.
Zfish   792 ISNTTPDSTEEDSKDAVEDTTVVSESKLKKQ-------VMFVVQDDKNKEKLANGL--NDSDSVL 847

  Fly   815 TNTSQESRHETDHNNKQQYPAAALMPPPPPSLTNNHNHETIDEEEEVVIRPKARVPAVVKSANAQ 879
            .:.|..|.|:  .:|:...|  .|.|..||                             .|...:
Zfish   848 PHESNGSTHK--ESNEDMIP--PLSPTSPP-----------------------------MSPGFE 879

  Fly   880 GLTKEEIELRNLRKKTRKRTRKFEIDGVQMTTTTSRVIYGDDENGRI--YDDHDFRKQELRELKL 942
            |      ||...| .|.|:||||.:||.:::.|||:|:...|...::  |:    |:|||..|||
Zfish   880 G------ELHPSR-MTVKKTRKFMVDGREVSVTTSKVVSEGDSKEKLMRYN----RRQELHALKL 933

  Fly   943 LQKQEKKQQTELHLKEQQAKEQQDRRFEQERSSLEKTYEADMDMLARQHKQLVEKTEQTQENELR 1007
            ||::|:::..:|.||.||.:||..|..|||.:|.::.|:::::.|.:|::|...:.|....::||
Zfish   934 LQREEQREHAQLELKLQQQREQMFRHIEQEMTSKKQYYDSELERLEKQYQQQSGQMEAEHTSKLR 998

  Fly  1008 SSSKRIRSEQEQELKIFRENLKQEIRLLKQEVDLFPKDKRKDEFKQRRSAMELDHEEKERAFLDS 1072
            ..::||:::||:||                              .::.||::.|.:|::|.....
Zfish   999 EDARRIKAQQEKEL------------------------------SRKSSALKADPKEEQRFLQKQ 1033

  Fly  1073 LKERHELLLRRLSEKHRDHLATINRNFLQQKQNAMRTREALLWELEEKQLHERHQLSKRHVKELC 1137
            .:|.:|.|.:.:.| |:..:|::......:.|...|.|||::||||::.|.|::.|.|:.|||..
Zfish  1034 QQELNEALQKGVQE-HKRKVASMEWEITVKSQQLKRAREAVIWELEQRHLQEKYHLFKQQVKEQY 1097

  Fly  1138 FMQRHQMIIRHEKELDQVKRMLQRKEEDMVKKQTMEKRALPKRIRAERKARDLMFRESLRISTNL 1202
            .:||.|:..||.|:.::..|..|...|:....|..|:.:..|..:||.|:|....:..||.....
Zfish  1098 SLQRQQLTKRHNKDKERASRFQQSLLEEQKSLQAQERASFLKTQKAEAKSRLNQLKMELRKQGLS 1162

  Fly  1203 DPEIERDRLKKFQEQEKKRYMQEERRFEVKHQKQLEELRATRESAIKELEQLQNEKRRALVEHEH 1267
            .|| :|..|.:...:|:.|..||::..:..|:.||:.::...:::..||:||||||.:.||:.|.
Zfish  1163 GPE-QRQHLTQLLSEEEARQKQEKQSLQESHESQLKAVQEQCDASTAELQQLQNEKLQVLVDMEK 1226

  Fly  1268 SKLSEIDERLKGELREWREQLVPRKQELNRQIKLAIDQHEK 1308
            .|:..:::....||.|||::|..||:.|...  ||..:.||
Zfish  1227 KKIKALEDEHTLELNEWRDKLACRKEVLEED--LARRRREK 1265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slik	NP_726441.1	STKc_SLK_like	31..310	CDD:132942	159/278 (57%)
		S_TKc	37..295	CDD:214567	153/257 (60%)
		PKK	958..1095	CDD:289257	33/136 (24%)
		PKK	1126..1266	CDD:289257	44/139 (32%)
si:dkey-81j8.6	XP_005155384.1	PKc_like	28..307	CDD:328722	159/278 (57%)
		PKK	949..1056	CDD:315199	33/137 (24%)
		PKK	1086..1225	CDD:315199	44/139 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	354	1.000	Domainoid score	I953
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D365746at33208
OrthoFinder	1	1.000	-	-		FOG0002520
OrthoInspector	1	1.000	-	-		otm25957
orthoMCL	1	0.900	-	-		OOG6_105446
Panther	1	1.100	-	-	O	PTHR48012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.920