DRSC/TRiP Functional Genomics Resources

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Protein Alignment mAChR-A and HTR5A

DIOPT Version :10

Sequence 1:NP_523844.2 Gene:mAChR-A / 37892 FlyBaseID:FBgn0000037 Length:805 Species:Drosophila melanogaster
Sequence 2:NP_076917.1 Gene:HTR5A / 3361 HGNCID:5300 Length:357 Species:Homo sapiens


Alignment Length:52 Identity:14/52 - (26%)
Similarity:16/52 - (30%) Gaps:19/52 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   411 AVQEPLPVAR-----TSYSATPIAVEETDEAPVTDSTAHQEQTTDTVPVQDD 457
            |..||.|..|     |:||              .|.....|......|:|||
Human    43 ASMEPPPDPRKQCYSTTYS--------------EDYVPQYEYPPPACPLQDD 80

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mAChR-ANP_523844.2 7tmA_mAChR_DM1-like 105..>300 CDD:320428
TM helix 1 106..132 CDD:320428
TM helix 2 139..165 CDD:320428
TM helix 3 177..207 CDD:320428
TM helix 4 219..242 CDD:320428
TM helix 5 265..294 CDD:320428
7tm_GPCRs <707..783 CDD:475119
TM helix 6 716..738 CDD:410628
TM helix 7 751..776 CDD:410628
HTR5ANP_076917.1 7tmA_5-HT5 41..349 CDD:320451 14/52 (27%)
TM helix 1 42..68 CDD:320451 9/38 (24%)
TM helix 2 75..101 CDD:320451 4/6 (67%)
TM helix 3 114..144 CDD:320451
TM helix 4 156..177 CDD:320451
TM helix 5 197..226 CDD:320451
TM helix 6 278..308 CDD:320451
TM helix 7 317..342 CDD:320451
Blue background indicates that the domain is not in the aligned region.

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