Protein Alignment mAChR-A and Hrh4

DIOPT Version :9

• Sequence 1: NP_523844.2
• Gene: mAChR-A / 37892
• FlyBaseID: FBgn0000037
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: NP_694727.1
• Gene: Hrh4 / 225192
• MGIID: 2429635
• Length: 391
• Species: Mus musculus
• Alignment Length: 290
• Identity: 84/290 - (28%)
• Similarity: 134/290 - (46%)
• Gaps: 52/290 - (17%)

  Fly   102 ASMVVMGFVAAILSTVTVAGNVMVMISFKIDKQLQTISNYFLFSLAIADFAIGAISMPLFAVTTI 166
            |:.|.:.|:.:..:...:.||.:|:::|.:|:.|:..||||..:|||:||.:|.||:||: :..:
Mouse    13 AAQVPLAFLMSSFAFAIMVGNAVVILAFVVDRNLRHRSNYFFLNLAISDFLVGLISIPLY-IPHV 76

  Fly   167 LGYWPLGPIVCDTWLALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRT-TNRAAVMIGAAWG 230
            |..|..|..:|..||..|||...|||.|:::||:|||.||:..::|||:.| ..:....:.|.|.
Mouse    77 LFNWNFGSGICMFWLITDYLLCTASVYNIVLISYDRYQSVSNAVSYRAQHTGIMKIVAQMVAVWI 141

  Fly   231 ISLLLWPPWIY---SWPYIEGKRTVPKDECYIQFIETNQYITFGTALAAFYFPVTIMCF----LY 288
            ::.|:..|.|.   ||     |.:....:|...|: |..||...|.|..|..||..:.:    :|
Mouse   142 LAFLVNGPMILASDSW-----KNSTNTKDCEPGFV-TEWYILTITMLLEFLLPVISVAYFNVQIY 200

  Fly   289 WRIWRE-----------------------------TKKRQKDLPNLQAGKKDSSKRSNSSDENTV 324
            |.:|:.                             .:.....|....|.:...|.|..||...::
Mouse   201 WSLWKRRALSRCPSHAGFSTTSSSASGHLHRAGVACRTSNPGLKESAASRHSESPRRKSSILVSL 265

  Fly   325 VNHASGGLLAFAQVGGNDHDTWRRPRSESS 354
            ..|.:..:.|| :||    ..|   ||||:
Mouse   266 RTHMNSSITAF-KVG----SFW---RSESA 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-A	NP_523844.2	7tm_4	117..>241	CDD:304433	48/124 (39%)
		7tm_1	121..>314	CDD:278431	67/229 (29%)
Hrh4	NP_694727.1	7tm_1	32..360	CDD:278431	81/271 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..258		4/19 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010